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Literature summary extracted from

  • Pan, Y.; Yang, J.; Gong, Y.; Li, X.; Hu, H.
    3-Hydroxyisobutyryl-CoA hydrolase involved in isoleucine catabolism regulates triacylglycerol accumulation in Phaeodactylum tricornutum (2017), Philos. Trans. R. Soc. Lond. B Biol. Sci., 372, 20160409 .
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.2.4 (S)-3-hydroxyisobutyryl-CoA + H2O Phaeodactylum tricornutum
-
 CoA + (S)-3-hydroxyisobutyrate
-
 ir
3.1.2.4 3-hydroxypropionyl-CoA + H2O Phaeodactylum tricornutum
-
 CoA + 3-hydroxypropionate
-
 ir

Organism

EC Number Organism UniProt Comment Textmining
3.1.2.4 Phaeodactylum tricornutum
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.2.4 (S)-3-hydroxyisobutyryl-CoA + H2O
-
 Phaeodactylum tricornutum CoA + (S)-3-hydroxyisobutyrate
-
 ir
3.1.2.4 3-hydroxypropionyl-CoA + H2O
-
 Phaeodactylum tricornutum CoA + 3-hydroxypropionate
-
 ir

Synonyms

EC Number Synonyms Comment Organism
3.1.2.4 HIBCH
-
 Phaeodactylum tricornutum

General Information

EC Number General Information Comment Organism
3.1.2.4 metabolism enzyme overexpression accelerates L-Ile degradation and triacylglycerol accumulation and results in a lowered L-Ile content Phaeodactylum tricornutum