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Literature summary extracted from

  • Xu, Y.; Sun, Z.
    Regulation of S-formylglutathione hydrolase by the anti-aging gene klotho (2017), Oncotarget, 8, 88259-88275 .
    View publication on PubMedView publication on EuropePMC

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.2.12 nucleus
-
 Mus musculus 5634
-
3.1.2.12 nucleus
-
 Homo sapiens 5634
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.2.12 S-formylglutathione + H2O Mus musculus
-
 glutathione + formate
-
 ?
3.1.2.12 S-formylglutathione + H2O Homo sapiens
-
 glutathione + formate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.2.12 Homo sapiens
-
-
-
3.1.2.12 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.2.12 erythrocyte
-
 Homo sapiens
-
3.1.2.12 HEK-293 cell
-
 Homo sapiens
-
3.1.2.12 kidney
-
 Mus musculus
-
3.1.2.12 mIMCD-3 cell
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.2.12 S-formylglutathione + H2O
-
 Mus musculus glutathione + formate
-
 ?
3.1.2.12 S-formylglutathione + H2O
-
 Homo sapiens glutathione + formate
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.2.12 ? x * 31000, SDS-PAGE Mus musculus
3.1.2.12 ? x * 31000, SDS-PAGE Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
3.1.2.12 FGH
-
 Mus musculus
3.1.2.12 FGH
-
 Homo sapiens

Expression

EC Number Organism Comment Expression
3.1.2.12 Mus musculus overexpression of short-form Klotho increases enzyme mRNA and protein expression up
3.1.2.12 Homo sapiens overexpression of short-form Klotho increases enzyme mRNA and protein expression up