BRENDA - Enzyme Database

Regulation of S-formylglutathione hydrolase by the anti-aging gene klotho

Xu, Y.; Sun, Z.; Oncotarget 8, 88259-88275 (2017)

Data extracted from this reference:

Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
3.1.2.12
nucleus
-
Homo sapiens
5634
-
3.1.2.12
nucleus
-
Mus musculus
5634
-
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
3.1.2.12
S-formylglutathione + H2O
Mus musculus
-
glutathione + formate
-
-
?
3.1.2.12
S-formylglutathione + H2O
Homo sapiens
-
glutathione + formate
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
3.1.2.12
Homo sapiens
-
-
-
3.1.2.12
Mus musculus
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
3.1.2.12
erythrocyte
-
Homo sapiens
-
3.1.2.12
HEK-293 cell
-
Homo sapiens
-
3.1.2.12
kidney
-
Mus musculus
-
3.1.2.12
mIMCD cell
-
Mus musculus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.1.2.12
S-formylglutathione + H2O
-
751775
Mus musculus
glutathione + formate
-
-
-
?
3.1.2.12
S-formylglutathione + H2O
-
751775
Homo sapiens
glutathione + formate
-
-
-
?
Subunits
EC Number
Subunits
Commentary
Organism
3.1.2.12
?
x * 31000, SDS-PAGE
Homo sapiens
3.1.2.12
?
x * 31000, SDS-PAGE
Mus musculus
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
3.1.2.12
nucleus
-
Homo sapiens
5634
-
3.1.2.12
nucleus
-
Mus musculus
5634
-
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
3.1.2.12
S-formylglutathione + H2O
Mus musculus
-
glutathione + formate
-
-
?
3.1.2.12
S-formylglutathione + H2O
Homo sapiens
-
glutathione + formate
-
-
?
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
3.1.2.12
erythrocyte
-
Homo sapiens
-
3.1.2.12
HEK-293 cell
-
Homo sapiens
-
3.1.2.12
kidney
-
Mus musculus
-
3.1.2.12
mIMCD cell
-
Mus musculus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.1.2.12
S-formylglutathione + H2O
-
751775
Mus musculus
glutathione + formate
-
-
-
?
3.1.2.12
S-formylglutathione + H2O
-
751775
Homo sapiens
glutathione + formate
-
-
-
?
Subunits (protein specific)
EC Number
Subunits
Commentary
Organism
3.1.2.12
?
x * 31000, SDS-PAGE
Homo sapiens
3.1.2.12
?
x * 31000, SDS-PAGE
Mus musculus
Expression
EC Number
Organism
Commentary
Expression
3.1.2.12
Homo sapiens
overexpression of short-form Klotho increases enyzme mRNA and protein expression
up
3.1.2.12
Mus musculus
overexpression of short-form Klotho increases enyzme mRNA and protein expression
up
Expression (protein specific)
EC Number
Organism
Commentary
Expression
3.1.2.12
Homo sapiens
overexpression of short-form Klotho increases enyzme mRNA and protein expression
up
3.1.2.12
Mus musculus
overexpression of short-form Klotho increases enyzme mRNA and protein expression
up