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Literature summary extracted from

  • Jing, F.; Zhao, L.; Yandeau-Nelson, M.D.; Nikolau, B.J.
    Two distinct domains contribute to the substrate acyl chain length selectivity of plant acyl-ACP thioesterase (2018), Nat. Commun., 9, 860 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.1.2.14 expressed in Escherichia coli strain K27 Cuphea viscosissima

Protein Variants

EC Number Protein Variants Comment Organism
3.1.2.14 A276P/D282N/L289F the mutation significantly increases the fatty acid titer of the mutant strain Cuphea viscosissima
3.1.2.14 I260L the mutation significantly increases (by up to 3.5fold) the fatty acid titer of the mutant strain Cuphea viscosissima
3.1.2.14 L257F the mutation significantly increases (by up to 3.5fold) the fatty acid titer of the mutant strain Cuphea viscosissima
3.1.2.14 L289F the mutation significantly increases (by up to 2fold) the fatty acid titer of the mutant strain Cuphea viscosissima
3.1.2.14 V194F the mutant of isoform FatB2 displays distinct substrate specificity toward 4- to 8-carbon acyl-[acyl-carrier protein] Cuphea viscosissima

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.2.14 an oleoyl-[acyl-carrier protein] + H2O Cuphea viscosissima
-
an [acyl-carrier protein] + oleate
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.1.2.14 Cuphea viscosissima G3ESU9
-
-
3.1.2.14 Cuphea viscosissima G3ESV0
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.2.14 an oleoyl-[acyl-carrier protein] + H2O
-
Cuphea viscosissima an [acyl-carrier protein] + oleate
-
?
3.1.2.14 decanoyl-[acyl-carrier protein] + H2O substrate for isoform FatB1 Cuphea viscosissima [acyl-carrier protein] + decanoate
-
?
3.1.2.14 myristoyl-[acyl-carrier protein] + H2O substrate for isoform FatB2 Cuphea viscosissima [acyl-carrier protein] + myristate
-
?
3.1.2.14 nonanoyl-[acyl-carrier protein] + H2O substrate for isoform FatB1 Cuphea viscosissima [acyl-carrier protein] + nonanoate
-
?
3.1.2.14 octanoyl-[acyl-carrier protein] + H2O substrate for isoform FatB1 Cuphea viscosissima [acyl-carrier protein] + octanoate
-
?
3.1.2.14 palmitoyl-[acyl-carrier protein] + H2O substrate for isoform FatB2 Cuphea viscosissima [acyl-carrier protein] + palmitate
-
?

Synonyms

EC Number Synonyms Comment Organism
3.1.2.14 acyl-ACP-thioesterase
-
Cuphea viscosissima
3.1.2.14 FATB1 isoform Cuphea viscosissima
3.1.2.14 FatB2 isoform Cuphea viscosissima