Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Liu, D.; Wei, Y.; Liu, X.; Zhou, Y.; Jiang, L.; Yin, J.; Wang, F.; Hu, Y.; Nanjaraj Urs, A.N.; Liu, Y.; Ang, E.L.; Zhao, S.; Zhao, H.; Zhang, Y.
    Indoleacetate decarboxylase is a glycyl radical enzyme catalysing the formation of malodorant skatole (2018), Nat. Commun., 9, 4224 .
    View publication on PubMedView publication on EuropePMC

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
4.1.1.115 homology modeling of structure and docking of the indoleacetate substrate Tractidigestivibacter scatoligenes

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1.1.115 0.358
-
(1H-indol-3-yl)acetate pH 7.5, 30°C Clostridium scatologenes
4.1.1.115 0.37
-
(1H-indol-3-yl)acetate pH 7.5, 30°C Tractidigestivibacter scatoligenes

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.1.115 (1H-indol-3-yl)acetate Tractidigestivibacter scatoligenes
-
skatole + CO2
-
?
4.1.1.115 (1H-indol-3-yl)acetate Clostridium scatologenes
-
skatole + CO2
-
?
4.1.1.115 additional information Tractidigestivibacter scatoligenes no substrates: phenylacetate or p-hydroxyphenylacetate ?
-
?
4.1.1.115 additional information Clostridium scatologenes no substrates: phenylacetate or p-hydroxyphenylacetate ?
-
?

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.115 Clostridium scatologenes A0A0E3M8P3
-
-
4.1.1.115 Tractidigestivibacter scatoligenes A0A100YXA1
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.115 (1H-indol-3-yl)acetate
-
Tractidigestivibacter scatoligenes skatole + CO2
-
?
4.1.1.115 (1H-indol-3-yl)acetate
-
Clostridium scatologenes skatole + CO2
-
?
4.1.1.115 additional information no substrates: phenylacetate or p-hydroxyphenylacetate Tractidigestivibacter scatoligenes ?
-
?
4.1.1.115 additional information no substrates: phenylacetate or p-hydroxyphenylacetate Clostridium scatologenes ?
-
?

Synonyms

EC Number Synonyms Comment Organism
4.1.1.115 AUL39_03420
-
Tractidigestivibacter scatoligenes
4.1.1.115 CSCA_1772
-
Clostridium scatologenes

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
4.1.1.115 2
-
(1H-indol-3-yl)acetate pH 7.5, 30°C Tractidigestivibacter scatoligenes
4.1.1.115 130
-
(1H-indol-3-yl)acetate pH 7.5, 30°C Clostridium scatologenes

General Information

EC Number General Information Comment Organism
4.1.1.115 physiological function indoleacetate decarboxylase is an O2-sensitive glycyl radical enzyme catalysing the decarboxylation of indoleacetate to form skatole as the terminal step of tryptophan fermentation in certain anaerobic bacteria Tractidigestivibacter scatoligenes
4.1.1.115 physiological function indoleacetate decarboxylase is an O2-sensitive glycyl radical enzyme catalysing the decarboxylation of indoleacetate to form skatole as the terminal step of tryptophan fermentation in certain anaerobic bacteria Clostridium scatologenes