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Literature summary extracted from

  • Zhu, Y.; Wang, W.L.; Yu, D.; Ouyang, Q.; Lu, Y.; Mao, Y.
    Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome (2018), Nat. Commun., 9, 1360 .
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.6.1.5 ATP + H2O + polypeptide Homo sapiens
-
 ADP + phosphate + unfolded polypeptide
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
5.6.1.5 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
5.6.1.5 NeutrAvidin agarose column chromatography and Superose 6 gel filtration Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
5.6.1.5 HEK-293 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.6.1.5 ATP + H2O + polypeptide
-
 Homo sapiens ADP + phosphate + unfolded polypeptide
-
 ?

Subunits

EC Number Subunits Comment Organism
5.6.1.5 heterohexamer
-
 Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
5.6.1.5 AAA-ATPase unfoldase
-
 Homo sapiens
5.6.1.5 Rpt
-
 Homo sapiens