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Literature summary extracted from

  • Citores, L.; Iglesias, R.; Gay, C.; Ferreras, J.M.
    Antifungal activity of the ribosome-inactivating protein BE27 from sugar beet (Beta vulgaris L.) against the green mould Penicillium digitatum (2016), Mol. Plant Pathol., 17, 261-271 .
    View publication on PubMedView publication on EuropePMC

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.2.2.22 apoplast
-
 Beta vulgaris subsp. vulgaris 48046
-

Organism

EC Number Organism UniProt Comment Textmining
3.2.2.22 Beta vulgaris subsp. vulgaris Q5QHN9
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.2.2.22 leaf
-
 Beta vulgaris subsp. vulgaris
-

Synonyms

EC Number Synonyms Comment Organism
3.2.2.22 BE27
-
 Beta vulgaris subsp. vulgaris
3.2.2.22 ribosome-inactivating protein
-
 Beta vulgaris subsp. vulgaris

General Information

EC Number General Information Comment Organism
3.2.2.22 physiological function BE27 displays antifungal activity against the green mould Penicillium digitatum. BE27 is able to enter into the cytosol and kill fungal cells. The mechanism of action seems to involve ribosomal RNA N-glycosylase activity on the sarcin-ricin loop of the major rRNA which inactivates irreversibly the fungal ribosomes. A structural motif composed of an alpha-helix and a beta-hairpin at the C-terminus of BE27 might contribute to the interaction with the fungal plasma membranes Beta vulgaris subsp. vulgaris