Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Nautiyal, A.; Rani, P.S.; Sharples, G.J.; Muniyappa, K.
    Mycobacterium tuberculosis RuvX is a Holliday junction resolvase formed by dimerisation of the monomeric YqgF nuclease domain (2016), Mol. Microbiol., 100, 656-674 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.1.21.10
-
 Mycobacterium tuberculosis

Protein Variants

EC Number Protein Variants Comment Organism
3.1.21.10 D28N mutation reduced its ability to cleave Holliday junction DNA Mycobacterium tuberculosis

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.21.10 Mg2+ the enzyme requires a divalent cation for Holliday junction cleavage (typically Mg2+ or Mn2+), but not for Holliday junction binding activity Mycobacterium tuberculosis
3.1.21.10 Mn2+ the enzyme requires a divalent cation for Holliday junction cleavage (typically Mg2+ or Mn2+), but not for Holliday junction binding activity Mycobacterium tuberculosis

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.21.10 50000
-
 gel filtration Mycobacterium tuberculosis

Organism

EC Number Organism UniProt Comment Textmining
3.1.21.10 Mycobacterium tuberculosis P9WGV7
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.21.10
-
 Mycobacterium tuberculosis

Subunits

EC Number Subunits Comment Organism
3.1.21.10 homodimer
-
 Mycobacterium tuberculosis

Synonyms

EC Number Synonyms Comment Organism
3.1.21.10 RuvX Holliday junction resolvase formed by dimerisation of the monomeric YqgF nuclease domain Mycobacterium tuberculosis

Expression

EC Number Organism Comment Expression
3.1.21.10 Mycobacterium tuberculosis expression is induced in response to DNA damage up