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Literature summary extracted from
- Molecular phenotype of tissue-nonspecific alkaline phosphatase with a proline (108) to leucine substitution associated with dominant odontohypophosphatasia (2015), Mol. Genet. Metab., 115, 180-185 .
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 3.1.3.1 | expressed in Tet-On CHO cells | Homo sapiens |
Protein Variants
| EC Number | Protein Variants | Comment | Organism |
|---|---|---|---|
| 3.1.3.1 | P108L | inactive, the mutation is associated with dominant odontohypophosphatasia | Homo sapiens |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.3.1 | Homo sapiens | P05186 | - |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.3.1 | 4-nitrophenyl phosphate + H2O | - |
Homo sapiens | 4-nitrophenol + phosphate | - |
? |  |
| 3.1.3.1 | alpha-naphthyl phosphate + H2O | - |
Homo sapiens | alpha-naphthol + phosphate | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.1.3.1 | homodimer | 2 * 80000, SDS-PAGE | Homo sapiens |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.1.3.1 | ALP | - |
Homo sapiens |
| 3.1.3.1 | tissue-nonspecific alkaline phosphatase | - |
Homo sapiens |
| 3.1.3.1 | TNSALP | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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