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Literature summary extracted from

  • Mahalapbutr, P.; Chusuth, P.; Kungwan, N.; Chavasiri, W.; Wolschann, P.; Rungrotmongkol, T.
    Molecular recognition of naphthoquinone-containing compounds against human DNA topoisomerase IIalpha ATPase domain A molecular modeling study (2017), J. Mol. Liq., 247, 374-385 .
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
5.6.2.2 1,4-benzoquinone
-
 Homo sapiens
5.6.2.2 3,8-dimethyl-5-(propan-2-yl)-6-[(prop-2-en-1-yl)oxy]naphthalene-1,2-dione
-
 Homo sapiens
5.6.2.2 3,8-dimethyl-6-(octyloxy)-5-(propan-2-yl)naphthalene-1,2-dione
-
 Homo sapiens
5.6.2.2 3,8-dimethyl-6-[(3-methylbut-2-en-1-yl)oxy]-5-(propan-2-yl)naphthalene-1,2-dione
-
 Homo sapiens
5.6.2.2 3,8-dimethyl-6-[[(2Z)-3-phenylprop-2-en-1-yl]oxy]-5-(propan-2-yl)naphthalene-1,2-dione
-
 Homo sapiens
5.6.2.2 4,7-dimethyl-5,6-dioxo-1-(propan-2-yl)-5,6-dihydronaphthalen-2-yl 2-chlorobenzoate
-
 Homo sapiens
5.6.2.2 4,7-dimethyl-5,6-dioxo-1-(propan-2-yl)-5,6-dihydronaphthalen-2-yl 2-methoxybenzoate
-
 Homo sapiens
5.6.2.2 4,7-dimethyl-5,6-dioxo-1-(propan-2-yl)-5,6-dihydronaphthalen-2-yl 4-methoxybenzoate
-
 Homo sapiens
5.6.2.2 4,7-dimethyl-5,6-dioxo-1-(propan-2-yl)-5,6-dihydronaphthalen-2-yl benzoate
-
 Homo sapiens
5.6.2.2 4,7-dimethyl-5,6-dioxo-1-(propan-2-yl)-5,6-dihydronaphthalen-2-yl butanoate
-
 Homo sapiens
5.6.2.2 4,7-dimethyl-5,6-dioxo-1-(propan-2-yl)-5,6-dihydronaphthalen-2-yl decanoate
-
 Homo sapiens
5.6.2.2 4,7-dimethyl-5,6-dioxo-1-(propan-2-yl)-5,6-dihydronaphthalen-2-yl hexanoate
-
 Homo sapiens
5.6.2.2 4,7-dimethyl-5,6-dioxo-1-(propan-2-yl)-5,6-dihydronaphthalen-2-yl octanoate
-
 Homo sapiens
5.6.2.2 6-(benzyloxy)-3,8-dimethyl-5-(propan-2-yl)naphthalene-1,2-dione
-
 Homo sapiens
5.6.2.2 6-(dodecyloxy)-3,8-dimethyl-5-(propan-2-yl)naphthalene-1,2-dione
-
 Homo sapiens
5.6.2.2 6-butoxy-3,8-dimethyl-5-(propan-2-yl)naphthalene-1,2-dione
-
 Homo sapiens
5.6.2.2 6-ethoxy-3,8-dimethyl-5-(propan-2-yl)naphthalene-1,2-dione
-
 Homo sapiens
5.6.2.2 6-methoxy-3,8-dimethyl-5-(propan-2-yl)naphthalene-1,2-dione
-
 Homo sapiens
5.6.2.2 6-[[(2E)-3,7-dimethylocta-2,6-dien-1-yl]oxy]-3,8-dimethyl-5-(propan-2-yl)naphthalene-1,2-dione
-
 Homo sapiens
5.6.2.2 salvicine
-
 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
5.6.2.2 Homo sapiens P11388
-
-

Synonyms

EC Number Synonyms Comment Organism
5.6.2.2 DNA topoisomerase IIalpha
-
 Homo sapiens
5.6.2.2 topoIIalpha
-
 Homo sapiens