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Literature summary extracted from
- Phosphatidic acid phosphatase, a key enzyme in the regulation of lipid synthesis (2009), J. Biol. Chem., 284, 2593-2597 .
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.3.4 | cardiolipin | - |
Saccharomyces cerevisiae |  |
| 3.1.3.4 | CDP-diacylglycerol | - |
Saccharomyces cerevisiae | |
| 3.1.3.4 | phosphatidylinositol | - |
Saccharomyces cerevisiae | |
Protein Variants
| EC Number | Protein Variants | Comment | Organism |
|---|---|---|---|
| 3.1.3.4 | D398E | inactive | Saccharomyces cerevisiae |
| 3.1.3.4 | D400E | inactive | Saccharomyces cerevisiae |
| 3.1.3.4 | G80R | inactive | Saccharomyces cerevisiae |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.1.3.4 | cytosol | - |
Saccharomyces cerevisiae | 5829 | - |
| 3.1.3.4 | membrane | - |
Saccharomyces cerevisiae | 16020 | - |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.3.4 | Mg2+ | dependent on | Saccharomyces cerevisiae | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.3.4 | 1,2-diacylglycerol 3-phosphate + H2O | Saccharomyces cerevisiae | - |
1,2-diacyl-sn-glycerol + phosphate | - |
ir | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.3.4 | Saccharomyces cerevisiae | - |
- |
- |
Posttranslational Modification
| EC Number | Posttranslational Modification | Comment | Organism |
|---|---|---|---|
| 3.1.3.4 | phosphoprotein | the enzyme is phosphorylated by cyclin-dependent kinase 1 | Saccharomyces cerevisiae |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.3.4 | 1,2-diacylglycerol 3-phosphate + H2O | - |
Saccharomyces cerevisiae | 1,2-diacyl-sn-glycerol + phosphate | - |
ir | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.1.3.4 | monomer | 1 * 124000, SDS-PAGE | Saccharomyces cerevisiae |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.1.3.4 | 3-sn-phosphatidate phosphohydrolase | - |
Saccharomyces cerevisiae |
| 3.1.3.4 | lipin | - |
Saccharomyces cerevisiae |
| 3.1.3.4 | PA2 phosphatase | - |
Saccharomyces cerevisiae |
| 3.1.3.4 | pah1 | - |
Saccharomyces cerevisiae |
| 3.1.3.4 | PAP3 | - |
Saccharomyces cerevisiae |
| 3.1.3.4 | SMP2 | - |
Saccharomyces cerevisiae |
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Release 2023.1 (January 2023)
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