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Literature summary extracted from

  • Horinouchi, S.; Suzuki, H.; Nishiyama, M.; Beppu, T.
    Nucleotide sequence and transcriptional analysis of the Streptomyces griseus gene (afsA) responsible for A-factor biosynthesis (1989), J. Bacteriol., 171, 1206-1210 .
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.277 a medium-chain 3-oxoacyl-[acyl-carrier protein] + glycerone phosphate Streptomyces griseus key enzyme for A-factor (2-isocapryloyl-3R-hydroxymethyl-y-butyrolactone) biosynthesis 2-oxo-3-(phosphooxy)propyl 3-oxoalkanoate + a holo-[acyl-carrier protein]
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?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.277 Streptomyces griseus P18394
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-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.277 a medium-chain 3-oxoacyl-[acyl-carrier protein] + glycerone phosphate
-
Streptomyces griseus 2-oxo-3-(phosphooxy)propyl 3-oxoalkanoate + a holo-[acyl-carrier protein]
-
?
2.3.1.277 a medium-chain 3-oxoacyl-[acyl-carrier protein] + glycerone phosphate key enzyme for A-factor (2-isocapryloyl-3R-hydroxymethyl-y-butyrolactone) biosynthesis Streptomyces griseus 2-oxo-3-(phosphooxy)propyl 3-oxoalkanoate + a holo-[acyl-carrier protein]
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?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.277 afsA
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Streptomyces griseus

General Information

EC Number General Information Comment Organism
2.3.1.277 metabolism key enzyme for A-factor (2-isocapryloyl-3R-hydroxymethyl-y-butyrolactone) biosynthesis Streptomyces griseus