EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.3.1.286 | nicotinamide | - |
Archaeoglobus fulgidus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.286 | [protein]-N6-acetyl-L-lysine + NAD+ | Archaeoglobus fulgidus | - |
[protein]-N6-[1,1-(5-adenosylyl-alpha-D-ribose-1,2-di-O-yl)ethyl]-L-lysine + nicotinamide | - |
? | |
2.3.1.286 | [protein]-N6-acetyl-L-lysine + NAD+ + H2O | Archaeoglobus fulgidus | overall reaction | [protein]-L-lysine + 2''-O-acetyl-ADP-D-ribose + nicotinamide | - |
? | |
2.3.1.286 | [protein]-N6-[1,1-(5-adenosylyl-alpha-D-ribose-1,2-di-O-yl)ethyl]-L-lysine + H2O | Archaeoglobus fulgidus | - |
[protein]-L-lysine + 2''-O-acetyl-ADP-D-ribose | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.1.286 | Archaeoglobus fulgidus | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.286 | HLKSKKGQSTSRHK(K-Ac)LMFK + NAD+ + H2O | p53A peptide | Archaeoglobus fulgidus | HLKSKKGQSTSRHKKLMFK + 2''-O-acetyl-ADP-D-ribose + nicotinamide | - |
? | |
2.3.1.286 | [protein]-N6-acetyl-L-lysine + NAD+ | - |
Archaeoglobus fulgidus | [protein]-N6-[1,1-(5-adenosylyl-alpha-D-ribose-1,2-di-O-yl)ethyl]-L-lysine + nicotinamide | - |
? | |
2.3.1.286 | [protein]-N6-acetyl-L-lysine + NAD+ + H2O | overall reaction | Archaeoglobus fulgidus | [protein]-L-lysine + 2''-O-acetyl-ADP-D-ribose + nicotinamide | - |
? | |
2.3.1.286 | [protein]-N6-[1,1-(5-adenosylyl-alpha-D-ribose-1,2-di-O-yl)ethyl]-L-lysine + H2O | - |
Archaeoglobus fulgidus | [protein]-L-lysine + 2''-O-acetyl-ADP-D-ribose | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.3.1.286 | Af2Sir2 | - |
Archaeoglobus fulgidus |
2.3.1.286 | Sir2 | - |
Archaeoglobus fulgidus |
2.3.1.286 | sirtuin | - |
Archaeoglobus fulgidus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
2.3.1.286 | NAD+ | - |
Archaeoglobus fulgidus |