Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Adzic, M.; Nedeljkovic, N.
    Unveiling the role of ecto-5'-nucleotidase/CD73 in astrocyte migration by using pharmacological tools (2018), Front. Pharmacol., 9, 153 .
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.3.5 alpha,beta-methylene ADP
-
 Rattus norvegicus
3.1.3.5 additional information not inhibited by levamisole Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.3.5 membrane
-
 Rattus norvegicus 16020
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.3.5 Mg2+ 1.8 mM used in assay conditions Rattus norvegicus
3.1.3.5 Zn2+ a Zn2+-binding enzyme Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.5 Rattus norvegicus
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.1.3.5 glycoprotein
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.3.5 astrocyte
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.5 5'-AMP + H2O most efficiently hydrolyzed substrate Rattus norvegicus adenosine + phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.3.5 CD73 a bifunctional glycosylphosphatidylinositol-anchored membrane protein which functions as ecto-5'-nucleotidase and a membrane receptor for extracellular matrix protein Rattus norvegicus
3.1.3.5 ecto-5'-nucleotidase
-
 Rattus norvegicus
3.1.3.5 eNT
-
 Rattus norvegicus

Expression

EC Number Organism Comment Expression
3.1.3.5 Rattus norvegicus after scratch wounding, the abundance of enzyme mRNA increases more than 2fold up