Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Agnew, T.; Munnur, D.; Crawford, K.; Palazzo, L.; Mikoc, A.; Ahel, I.
    MacroD1 is a promiscuous ADP-ribosyl hydrolase localized to mitochondria (2018), Front. Microbiol., 9, 20 .
    View publication on PubMedView publication on EuropePMC

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.1.106 mitochondrion
-
 Homo sapiens 5739
-
3.1.1.106 mitochondrion
-
 Mus musculus 5739
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.106 2''-O-acetyl-ADP-D-ribose + H2O Homo sapiens
-
 ADP-D-ribose + acetate
-
 ?
3.1.1.106 2''-O-acetyl-ADP-D-ribose + H2O Mus musculus
-
 ADP-D-ribose + acetate
-
 ?
3.1.1.106 3''-O-acetyl-ADP-D-ribose + H2O Homo sapiens
-
 ADP-D-ribose + acetate
-
 ?
3.1.1.106 3''-O-acetyl-ADP-D-ribose + H2O Mus musculus
-
 ADP-D-ribose + acetate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.106 Homo sapiens
-
-
-
3.1.1.106 Mus musculus Q922B1
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.106 heart
-
 Homo sapiens
-
3.1.1.106 heart
-
 Mus musculus
-
3.1.1.106 HeLa cell
-
 Homo sapiens
-
3.1.1.106 skeletal muscle highest expression Homo sapiens
-
3.1.1.106 skeletal muscle highest expression Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.106 2''-O-acetyl-ADP-D-ribose + H2O
-
 Homo sapiens ADP-D-ribose + acetate
-
 ?
3.1.1.106 2''-O-acetyl-ADP-D-ribose + H2O
-
 Mus musculus ADP-D-ribose + acetate
-
 ?
3.1.1.106 3''-O-acetyl-ADP-D-ribose + H2O
-
 Homo sapiens ADP-D-ribose + acetate
-
 ?
3.1.1.106 3''-O-acetyl-ADP-D-ribose + H2O
-
 Mus musculus ADP-D-ribose + acetate
-
 ?
3.1.1.106 mono-ADP-ribosylated phosphorylated double stranded DNA ends + H2O the enzyme can efficiently remove ADP-D-ribose from 5' and 3'-phosphorylated double stranded DNA adducts in vitro Homo sapiens ?
-
 ?
3.1.1.106 mono-ADP-ribosylated phosphorylated double stranded DNA ends + H2O the enzyme can efficiently remove ADP-D-ribose from 5' and 3'-phosphorylated double stranded DNA adducts in vitro Mus musculus ?
-
 ?
3.1.1.106 additional information no activity with ADP-ribosylated thymidine on single stranded DNA Homo sapiens ?
-
 ?
3.1.1.106 additional information no activity with ADP-ribosylated thymidine on single stranded DNA Mus musculus ?
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.1.106 ? x * 28000, SDS-PAGE Homo sapiens
3.1.1.106 ? x * 28000, SDS-PAGE Mus musculus

Synonyms

EC Number Synonyms Comment Organism
3.1.1.106 ADP-ribosyl hydrolase
-
 Homo sapiens
3.1.1.106 ADP-ribosyl hydrolase
-
 Mus musculus
3.1.1.106 MACROD1
-
 Homo sapiens
3.1.1.106 MACROD1
-
 Mus musculus