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Literature summary extracted from

  • Kawai, A.; Higuchi, S.; Tsunoda, M.; Nakamura, K.T.; Yamagata, Y.; Miyamoto, S.
    Crystal structure of family 4 uracil-DNA glycosylase from Sulfolobus tokodaii and a function of tyrosine 170 in DNA binding (2015), FEBS Lett., 589, 2675-2682 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.2.2.27 expressed in Escherichia coli Sulfurisphaera tokodaii

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
3.2.2.27 free enzyme and in complex with uracil Sulfurisphaera tokodaii

Protein Variants

EC Number Protein Variants Comment Organism
3.2.2.27 L169A the mutant retains most of the wild type activity Sulfurisphaera tokodaii
3.2.2.27 N171A the mutant retains most of the wild type activity Sulfurisphaera tokodaii
3.2.2.27 Y170A inactive Sulfurisphaera tokodaii

Organism

EC Number Organism UniProt Comment Textmining
3.2.2.27 Sulfurisphaera tokodaii Q96YD0
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.2.2.27
-
 Sulfurisphaera tokodaii

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.2.27 uracil-containing DNA + H2O
-
 Sulfurisphaera tokodaii uracil + DNA with abasic site
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.2.2.27 family 4 uracil-DNA glycosylase
-
 Sulfurisphaera tokodaii
3.2.2.27 UDG
-
 Sulfurisphaera tokodaii