Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Freitas-Mesquita, A.L.; Meyer-Fernandes, J.R.
    3'nucleotidase/nuclease in protozoan parasites Molecular and biochemical properties and physiological roles (2017), Exp. Parasitol., 179, 1-6 .
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.3.6 a 3'-ribonucleotide + H2O Leishmania amazonensis
-
 a ribonucleoside + phosphate
-
 ?
3.1.3.6 a 3'-ribonucleotide + H2O Crithidia sp.
-
 a ribonucleoside + phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.6 Crithidia sp.
-
-
-
3.1.3.6 Leishmania amazonensis
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.6 3'-AMP + H2O
-
 Leishmania amazonensis adenosine + phosphate
-
 ?
3.1.3.6 3'-AMP + H2O
-
 Crithidia sp. adenosine + phosphate
-
 ?
3.1.3.6 a 3'-ribonucleotide + H2O
-
 Leishmania amazonensis a ribonucleoside + phosphate
-
 ?
3.1.3.6 a 3'-ribonucleotide + H2O
-
 Crithidia sp. a ribonucleoside + phosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.3.6 ? x * 40000, SDS-PAGE Leishmania amazonensis
3.1.3.6 ? x * 40000, SDS-PAGE Crithidia sp.

Synonyms

EC Number Synonyms Comment Organism
3.1.3.6 3'-nucleotidase/nuclease
-
 Leishmania amazonensis
3.1.3.6 3'-nucleotidase/nuclease
-
 Crithidia sp.
3.1.3.6 3'NT/NU
-
 Leishmania amazonensis
3.1.3.6 3'NT/NU
-
 Crithidia sp.

Expression

EC Number Organism Comment Expression
3.1.3.6 Leishmania amazonensis the activity and expression of the enzyme are increased when the parasites are submitted to purine starvation up

General Information

EC Number General Information Comment Organism
3.1.3.6 physiological function the enzyme plays a role in parasite escape from neutrophil extracellular traps, one of the first mechanisms of the host immune system for preventing infection Leishmania amazonensis