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Literature summary extracted from

  • Uddin, R.; Zahra, N.; Azam, S.
    Identification of glucosyl-3-phosphoglycerate phosphatase as a novel drug target against resistant strain of Mycobacterium tuberculosis (XDR1219) by using comparative metabolic pathway approach (2019), Comput. Biol. Chem., 79, 91-102 .
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.3.85 cytoplasm
-
 Mycobacterium tuberculosis 5737
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.3.85 2-O-(alpha-D-glucopyranosyl)-3-phospho-D-glycerate + H2O Mycobacterium tuberculosis
-
 2-O-(alpha-D-glucopyranosyl)-D-glycerate + phosphate
-
 ?
3.1.3.85 2-O-(alpha-D-glucopyranosyl)-3-phospho-D-glycerate + H2O Mycobacterium tuberculosis H37Rv
-
 2-O-(alpha-D-glucopyranosyl)-D-glycerate + phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.85 Mycobacterium tuberculosis P9WIC7
-
-
3.1.3.85 Mycobacterium tuberculosis H37Rv P9WIC7
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.85 2-O-(alpha-D-glucopyranosyl)-3-phospho-D-glycerate + H2O
-
 Mycobacterium tuberculosis 2-O-(alpha-D-glucopyranosyl)-D-glycerate + phosphate
-
 ?
3.1.3.85 2-O-(alpha-D-glucopyranosyl)-3-phospho-D-glycerate + H2O
-
 Mycobacterium tuberculosis H37Rv 2-O-(alpha-D-glucopyranosyl)-D-glycerate + phosphate
-
 ?
3.1.3.85 additional information the enzyme has residual mutase activity but it prefers glucosyl-3-phosphoglycerate over 2-phosphoglycerate as a substrate Mycobacterium tuberculosis ?
-
 ?
3.1.3.85 additional information the enzyme has residual mutase activity but it prefers glucosyl-3-phosphoglycerate over 2-phosphoglycerate as a substrate Mycobacterium tuberculosis H37Rv ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.3.85 GpgP
-
 Mycobacterium tuberculosis

General Information

EC Number General Information Comment Organism
3.1.3.85 metabolism the protein is involved in the biosynthesis of methylglucose lipopolysaccharides which regulate the biosynthesis of mycolic acid Mycobacterium tuberculosis