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Literature summary extracted from

  • James, A.M.; Hoogewijs, K.; Logan, A.; Hall, A.R.; Ding, S.; Fearnley, I.M.; Murphy, M.P.
    Non-enzymatic N-acetylation of lysine residues by acetylCoA often occurs via a proximal S-acetylated thiol intermediate sensitive to glyoxalase II (2017), Cell Rep., 18, 2105-2112 .
    View publication on PubMedView publication on EuropePMC

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.2.6 mitochondrion
-
Homo sapiens 5739
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.2.6 S-(2-hydroxyacyl)glutathione + H2O Homo sapiens
-
glutathione + a 2-hydroxycarboxylate
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.1.2.6 Homo sapiens Q16775
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.2.6 S-(2-hydroxyacyl)glutathione + H2O
-
Homo sapiens glutathione + a 2-hydroxycarboxylate
-
?
3.1.2.6 S-acetylglutathione + H2O
-
Homo sapiens acetate + glutathione
-
?

Synonyms

EC Number Synonyms Comment Organism
3.1.2.6 Glo2
-
Homo sapiens
3.1.2.6 glyoxalase II
-
Homo sapiens

General Information

EC Number General Information Comment Organism
3.1.2.6 metabolism the enzyme limits lysine N-acetylation and N-succinylation of mitochondrial proteins Homo sapiens