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Literature summary extracted from

  • Hata, K.; Tochigi, T.; Sato, I.; Kawamura, S.; Shiozaki, K.; Wada, T.; Takahashi, K.; Moriya, S.; Yamaguchi, K.; Hosono, M.; Miyagi, T.
    Increased sialidase activity in serum of cancer patients Identification of sialidase and inhibitor activities in human serum (2015), Cancer Sci., 106, 383-389 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.2.1.18 expressed in HEK-293 T cells Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.2.1.18 exosome
-
 Homo sapiens
-
-

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.18 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.2.1.18 octyl-Sepharose chromatography and Toyopearl HW-55F column chromatography Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.2.1.18 serum
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.18 4-methylumbelliferyl alpha-D-N-acetylneuraminic acid + H2O about 1% activity compared to ganglioside GD3 Homo sapiens 4-methylumbelliferone + alpha-D-N-acetylneuraminic acid
-
 ?
3.2.1.18 fetuin + H2O about 5% activity compared to ganglioside GD3 Homo sapiens ?
-
 ?
3.2.1.18 ganglioside GD3 + H2O 100% activity Homo sapiens N-acetylneuraminate + ganglioside GM3
-
 ?
3.2.1.18 ganglioside GM3 + H2O about 60% activity compared to ganglioside GD3 Homo sapiens N-acetylneuraminate + beta-D-galactosyl-(1->4)-beta-D-glucosylceramide
-
 ?
3.2.1.18 siallyllactose + H2O about 7% activity compared to ganglioside GD3 Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.2.1.18 Neu3
-
 Homo sapiens

Expression

EC Number Organism Comment Expression
3.2.1.18 Homo sapiens the enzyme activity is increased in serum of prostate cancer patients up