Literature summary extracted from

Shiraishi, M.; Ishino, S.; Cann, I.; Ishino, Y.
A functional endonuclease Q exists in the bacterial domain identification and characterization of endonuclease Q from Bacillus pumilus (2017), Biosci. Biotechnol. Biochem., 81, 931-937 .

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
3.1.21.B1	DNA + H2O	Bacillus pumilus	the enzyme recognizes uracil, xanthine, and the AP site in DNA, and is probably involved in a specific repair process for damaged bases	?	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.1.21.B1	Bacillus pumilus	A0A3G1H3K8	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.1.21.B1	DNA + H2O	the enzyme recognizes uracil, xanthine, and the AP site in DNA, and is probably involved in a specific repair process for damaged bases	Bacillus pumilus	?	-	?
3.1.21.B1	DNA + H2O	the enzyme exhibits cleavage activity on DNA substrates containing deoxyuridine (dU), deoxyinosine (dI), and AP sites generating 23, 24, 24-nt-fragment, respectively, corresponding to the damaged site both in dsDNA and ssDNA. Cleavage products are not detected when normal DNA is used as substrate	Bacillus pumilus	?	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
3.1.21.B1	BpuEndoQ	-	Bacillus pumilus

General Information

EC Number	General Information	Comment	Organism
3.1.21.B1	physiological function	the enzyme recognizes uracil, xanthine, and the AP site in DNA, and is probably involved in a specific repair process for damaged bases	Bacillus pumilus

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Release 2023.1 (January 2023)