BRENDA - Enzyme Database show

Fatty acid specificity of acyl-CoA synthetase in rat glomeruli

Morisaki, N.; Kanzaki, T.; Saito, Y.; Yoshida, S.; Biochim. Biophys. Acta 875, 311-315 (1986)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
6.2.1.3
arachidonate
inhibition of palmitoyl-CoA synthesis
Rattus norvegicus
6.2.1.3
eicosapentanoate
inhibition of palmitoyl-CoA synthesis
Rattus norvegicus
6.2.1.3
linoleate
inhibition of palmitoyl-CoA synthesis
Rattus norvegicus
6.2.1.3
linolenate
inhibition of palmitoyl-CoA synthesis
Rattus norvegicus
6.2.1.3
oleate
inhibition of palmitoyl-CoA synthesis
Rattus norvegicus
KM Value [mM]
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
6.2.1.3
0.0073
-
linolenate
-
Rattus norvegicus
6.2.1.3
0.0128
-
linoleate
-
Rattus norvegicus
6.2.1.3
0.0155
-
eicosapentaenoate
-
Rattus norvegicus
6.2.1.3
0.0193
-
arachidonate
-
Rattus norvegicus
6.2.1.3
0.0229
-
oleate
-
Rattus norvegicus
6.2.1.3
0.0455
-
palmitate
-
Rattus norvegicus
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
6.2.1.3
Rattus norvegicus
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
6.2.1.3
kidney
glomeruli
Rattus norvegicus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
6.2.1.3
ATP + arachidonate + CoA
-
750
Rattus norvegicus
AMP + diphosphate + arachidonoyl-CoA
-
-
-
-
6.2.1.3
ATP + eicosapentaenoate + CoA
-
750
Rattus norvegicus
AMP + diphosphate + eicosapentaenoyl-CoA
-
-
-
-
6.2.1.3
ATP + linoleate + CoA
-
750
Rattus norvegicus
AMP + diphosphate + linoleoyl-CoA
-
-
-
-
6.2.1.3
ATP + linolenate + CoA
-
750
Rattus norvegicus
AMP + diphosphate + linolenoyl-CoA
-
-
-
-
6.2.1.3
ATP + oleate + CoA
-
750
Rattus norvegicus
AMP + diphosphate + oleoyl-CoA
-
-
-
-
6.2.1.3
ATP + palmitate + CoA
-
750
Rattus norvegicus
AMP + diphosphate + palmitoyl-CoA
-
-
-
-
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
6.2.1.3
arachidonate
inhibition of palmitoyl-CoA synthesis
Rattus norvegicus
6.2.1.3
eicosapentanoate
inhibition of palmitoyl-CoA synthesis
Rattus norvegicus
6.2.1.3
linoleate
inhibition of palmitoyl-CoA synthesis
Rattus norvegicus
6.2.1.3
linolenate
inhibition of palmitoyl-CoA synthesis
Rattus norvegicus
6.2.1.3
oleate
inhibition of palmitoyl-CoA synthesis
Rattus norvegicus
KM Value [mM] (protein specific)
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
6.2.1.3
0.0073
-
linolenate
-
Rattus norvegicus
6.2.1.3
0.0128
-
linoleate
-
Rattus norvegicus
6.2.1.3
0.0155
-
eicosapentaenoate
-
Rattus norvegicus
6.2.1.3
0.0193
-
arachidonate
-
Rattus norvegicus
6.2.1.3
0.0229
-
oleate
-
Rattus norvegicus
6.2.1.3
0.0455
-
palmitate
-
Rattus norvegicus
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
6.2.1.3
kidney
glomeruli
Rattus norvegicus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
6.2.1.3
ATP + arachidonate + CoA
-
750
Rattus norvegicus
AMP + diphosphate + arachidonoyl-CoA
-
-
-
-
6.2.1.3
ATP + eicosapentaenoate + CoA
-
750
Rattus norvegicus
AMP + diphosphate + eicosapentaenoyl-CoA
-
-
-
-
6.2.1.3
ATP + linoleate + CoA
-
750
Rattus norvegicus
AMP + diphosphate + linoleoyl-CoA
-
-
-
-
6.2.1.3
ATP + linolenate + CoA
-
750
Rattus norvegicus
AMP + diphosphate + linolenoyl-CoA
-
-
-
-
6.2.1.3
ATP + oleate + CoA
-
750
Rattus norvegicus
AMP + diphosphate + oleoyl-CoA
-
-
-
-
6.2.1.3
ATP + palmitate + CoA
-
750
Rattus norvegicus
AMP + diphosphate + palmitoyl-CoA
-
-
-
-