EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
5.6.1.6 | phosphatidylserine | the enzyme requires phosphatidylserine for maximum ATPase activity | Homo sapiens |
EC Number | Cloned (Comment) | Organism |
---|---|---|
5.6.1.6 | expressed in D-727 cells | Homo sapiens |
EC Number | General Stability | Organism |
---|---|---|
5.6.1.6 | phosphatidylserine specifically stabilizes ATPase activity of the purified enzyme | Homo sapiens |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
5.6.1.6 | plasma membrane | - |
Homo sapiens | 5886 | - |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
5.6.1.6 | Mg2+ | 1.5 mM used in assay conditions | Homo sapiens |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
5.6.1.6 | 212000 | - |
gel filtration | Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
5.6.1.6 | ATP + H2O + closed Cl- channel | Homo sapiens | - |
ADP + phosphate + open Cl- channel | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
5.6.1.6 | Homo sapiens | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
5.6.1.6 | - |
Homo sapiens |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
5.6.1.6 | ATP + H2O + closed Cl- channel | - |
Homo sapiens | ADP + phosphate + open Cl- channel | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
5.6.1.6 | ABCC7 | - |
Homo sapiens |
5.6.1.6 | CFTR | - |
Homo sapiens |
5.6.1.6 | cystic fibrosis transmembrane conductance regulator | - |
Homo sapiens |
EC Number | Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|---|
5.6.1.6 | 22 | 25 | the enzyme, in the absence of lipid or nucleotide, is unstable at room temperature, losing approximately half its ATP hydrolysis activity over a 30 minute period. The melting temperature is 22.7°C | Homo sapiens |