EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.21.4.5 | 2,3,5,6-tetrachlorohydroquinone + 2 glutathione | Sphingobium chlorophenolicum | the enzyme converts tetrachlorohydroquinone to trichlorohydroquinone and trichlorohydroquinone to dichlorohydroquinone. The enzyme is involved in degradation of pentachlorophenol a widely used wood preservative | 2,3,6-trichlorohydroquinone + Cl- + glutathione disulfide | - |
? | |
1.21.4.5 | 2,3,6-trichlorohydroquinone + 2 glutathione | Sphingobium chlorophenolicum | the enzyme converts tetrachlorohydroquinone to trichlorohydroquinone and trichlorohydroquinone to dichlorohydroquinone. The enzyme is involved in degradation of pentachlorophenol, a widely used wood preservative | 2,6-dichlorohydroquinone + Cl- + glutathione disulfide | - |
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EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.21.4.5 | Sphingobium chlorophenolicum | Q03520 | - |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.21.4.5 | 2,3,5,6-tetrachlorohydroquinone + 2 glutathione | the enzyme converts tetrachlorohydroquinone to trichlorohydroquinone and trichlorohydroquinone to dichlorohydroquinone. The enzyme is involved in degradation of pentachlorophenol a widely used wood preservative | Sphingobium chlorophenolicum | 2,3,6-trichlorohydroquinone + Cl- + glutathione disulfide | - |
? | |
1.21.4.5 | 2,3,5,6-tetrachlorohydroquinone + 2 glutathione | the enzyme converts tetrachlorohydroquinone to trichlorohydroquinone and trichlorohydroquinone to dichlorohydroquinone. The enzyme binds the glutathione involved in the thioldisulfide exchange reaction very poorly and does not alter its pKa in order to improve its nucleophilicity. Remarkably, single-turnover kinetic studies show that the enzyme catalyzes this step by approximately 10000fold | Sphingobium chlorophenolicum | 2,3,6-trichlorohydroquinone + Cl- + glutathione disulfide | - |
? | |
1.21.4.5 | 2,3,6-trichlorohydroquinone + 2 glutathione | the enzyme converts tetrachlorohydroquinone to trichlorohydroquinone and trichlorohydroquinone to dichlorohydroquinone. The enzyme is involved in degradation of pentachlorophenol, a widely used wood preservative | Sphingobium chlorophenolicum | 2,6-dichlorohydroquinone + Cl- + glutathione disulfide | - |
? | |
1.21.4.5 | 2,3,6-trichlorohydroquinone + 2 glutathione | the enzyme converts tetrachlorohydroquinone to trichlorohydroquinone and trichlorohydroquinone to dichlorohydroquinone. The enzyme binds the glutathione involved in the thioldisulfide exchange reaction very poorly and does not alter its pKa in order to improve its nucleophilicity. Remarkably, single-turnover kinetic studies show that the enzyme catalyzes this step by approximately 10000fold | Sphingobium chlorophenolicum | 2,6-dichlorohydroquinone + Cl- + glutathione disulfide | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.21.4.5 | TCHQ dehalogenase | - |
Sphingobium chlorophenolicum |
EC Number | General Information | Comment | Organism |
---|---|---|---|
1.21.4.5 | metabolism | the enzyme is involved in degradation of pentachlorophenol | Sphingobium chlorophenolicum |