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Literature summary extracted from

  • Anand, C.; Garg, R.; Ghosh, S.; Nagaraja, V.
    A Sir2 family protein Rv1151c deacetylates HU to alter its DNA binding mode in Mycobacterium tuberculosis (2017), Biochem. Biophys. Res. Commun., 493, 1204-1209 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.1.286 expressed in Mycobacterium smegmatis mc2155 cells Mycobacterium tuberculosis

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.3.1.286 Mg2+ 1 mM used in assay conditions Mycobacterium tuberculosis

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.286 Mycobacterium tuberculosis
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.286 Ni-NTA column chromatography Mycobacterium tuberculosis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.286 [HU protein]-N6-acetyl-L-lysine + NAD+ + H2O overall reaction Mycobacterium tuberculosis [HU protein]-L-lysine + 2''-O-acetyl-ADP-D-ribose + nicotinamide
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.286 Rv1151c
-
 Mycobacterium tuberculosis
2.3.1.286 Sir2
-
 Mycobacterium tuberculosis

Cofactor

EC Number Cofactor Comment Organism Structure
2.3.1.286 NAD+
-
 Mycobacterium tuberculosis