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Literature summary extracted from

  • Marchan, R.
    GDPD5, a choline-generating enzyme and its novel role in tumor cell migration (2016), Arch. Toxicol., 90, 3143-3144 .
    View publication on PubMed

Application

EC Number Application Comment Organism
3.1.4.2 medicine enzyme inhibition represents a targeting strategy in the treatment of breast cancer Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.4.2 sn-glycero-3-phosphocholine + H2O Homo sapiens
-
 choline + sn-glycerol 3-phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.4.2 Homo sapiens Q8WTR4
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.4.2 breast cancer cell
-
 Homo sapiens
-
3.1.4.2 MCF-7 cell
-
 Homo sapiens
-
3.1.4.2 MDA-MB-231 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.4.2 sn-glycero-3-phosphocholine + H2O
-
 Homo sapiens choline + sn-glycerol 3-phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.4.2 EDI3 isoform Homo sapiens
3.1.4.2 GDE2 isoform Homo sapiens
3.1.4.2 GDPD5
-
 Homo sapiens
3.1.4.2 GDPD6
-
 Homo sapiens

General Information

EC Number General Information Comment Organism
3.1.4.2 physiological function the enzyme drives tumor cell migration Homo sapiens