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Literature summary extracted from

  • Kerrinnes, T.; Young, B.M.; Leon, C.; Roux, C.M.; Tran, L.; Atluri, V.L.; Winter, M.G.; Tsolis, R.M.
    Phospholipase A1 modulates the cell envelope phospholipid content of Brucella melitensis, contributing to polymyxin resistance and pathogenicity (2015), Antimicrob. Agents Chemother., 59, 6717-6724 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.1.1.32 expression in Escherichia coli Brucella melitensis bv. 1

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.1.32 periplasm
-
 Brucella melitensis bv. 1
-
-

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.32 Brucella melitensis bv. 1 Q8YC51
-
-
3.1.1.32 Brucella melitensis bv. 1 ATCC 23456 Q8YC51
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.32 phosphatidylethanolamine + H2O
-
 Brucella melitensis bv. 1 2-acylglycerophosphoethanolamine + a carboxylate
-
 ?
3.1.1.32 phosphatidylethanolamine + H2O
-
 Brucella melitensis bv. 1 ATCC 23456 2-acylglycerophosphoethanolamine + a carboxylate
-
 ?
3.1.1.32 Tween 20 + H2O
-
 Brucella melitensis bv. 1 oleate + ?
-
 ?
3.1.1.32 Tween 20 + H2O
-
 Brucella melitensis bv. 1 ATCC 23456 oleate + ?
-
 ?
3.1.1.32 Tween 80 + H2O
-
 Brucella melitensis bv. 1 oleate + ?
-
 ?
3.1.1.32 Tween 80 + H2O
-
 Brucella melitensis bv. 1 ATCC 23456 oleate + ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.1.32 BveA
-
 Brucella melitensis bv. 1

General Information

EC Number General Information Comment Organism
3.1.1.32 physiological function by lowering the phosphatidylethanolamine content of the cell envelope, BveA increases the resistance of Brucella melitensis to polymyxin B. BveA is required for survival and replication of Brucella melitensis in macrophages and for persistent infection in mice Brucella melitensis bv. 1