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Literature summary extracted from

  • Davidovich-Rikanati, R.; Shalev, L.; Baranes, N.; Meir, A.; Itkin, M.; Cohen, S.; Zimbler, K.; Portnoy, V.; Ebizuka, Y.; Shibuya, M.; Burger, Y.; Katzir, N.; Schaffer, A.A.; Lewinsohn, E.; Tadmor, Y.
    Recombinant yeast as a functional tool for understanding bitterness and cucurbitacin biosynthesis in watermelon (Citrullus spp.) (2015), Yeast, 32, 103-114 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
5.4.99.33 gene CcCDS2, DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic tree, functional recombinant expression in Saccharomyces cerevisiae Citrullus colocynthis
5.4.99.33 gene CpCDS2, DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic tree, functional recombinant expression in Saccharomyces cerevisiae Cucurbita pepo

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.4.99.33 (3S)-2,3-epoxy-2,3-dihydrosqualene Cucurbita pepo
-
cucurbitadienol
-
?
5.4.99.33 (3S)-2,3-epoxy-2,3-dihydrosqualene Citrullus colocynthis
-
cucurbitadienol
-
?

Organism

EC Number Organism UniProt Comment Textmining
5.4.99.33 Citrullus colocynthis A0A0D3QXV2
-
-
5.4.99.33 Cucurbita pepo Q6BE24
-
-
5.4.99.33 no activity in Citrullus lanatus var. lanatus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
5.4.99.33 fruit
-
Cucurbita pepo
-
5.4.99.33 fruit
-
Citrullus colocynthis
-
5.4.99.33 leaf
-
Citrullus colocynthis
-
5.4.99.33 root
-
Citrullus colocynthis
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.4.99.33 (3S)-2,3-epoxy-2,3-dihydrosqualene
-
Cucurbita pepo cucurbitadienol
-
?
5.4.99.33 (3S)-2,3-epoxy-2,3-dihydrosqualene
-
Citrullus colocynthis cucurbitadienol
-
?

Synonyms

EC Number Synonyms Comment Organism
5.4.99.33 CcCDS2
-
Citrullus colocynthis
5.4.99.33 CpCPQ
-
Cucurbita pepo