EC Number | Application | Comment | Organism |
---|---|---|---|
4.2.1.24 | synthesis | in addition to hemA and hemL, hemB, hemD, hemF, hemG and hemH are also major regulatory targets of the heme biosynthesis pathway. Up-regulation of hemD and hemF benefits ALA accumulation whereas overexpression of hemB, hemG and hemH diminishes ALA accumulation. By combinatorial overexpression of hemA, hemL,hemD and hemF with different copy-number plasmids, the titer of ALA can be improved to 3.25 g/l | Escherichia coli |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
4.2.1.24 | protoporphyrinogen IX | feedback inhibition by downstream intermediate | Escherichia coli |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.2.1.24 | Escherichia coli | - |
- |
- |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
4.2.1.24 | HemB | - |
Escherichia coli |