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Literature summary extracted from
- AtMRP1 gene of Arabidopsis encodes a glutathione S-conjugate pump Isolation and functional definition of a plant ATP-binding cassette transporter gene (1997), Proc. Natl. Acad. Sci. USA, 94, 8243-8248 .
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 7.6.2.3 | expressed in Saccharomyces cerevisiae ycf1DELTA mutants | Arabidopsis thaliana |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 7.6.2.3 | vacuolar membrane | - |
Arabidopsis thaliana | 5774 | - |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 7.6.2.3 | Mg2+ | required in form of Mg2+-ATP | Arabidopsis thaliana |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 7.6.2.3 | Arabidopsis thaliana | Q9C8G9 | - |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 7.6.2.3 | ATP + H2O + glutathione disulfide[side 1] | - |
Arabidopsis thaliana | ADP + phosphate + glutathione disulfide[side 2] | - |
? | |
| 7.6.2.3 | ATP + H2O + S-(2,4-dinitrophenyl)glutathione[side 1] | - |
Arabidopsis thaliana | ADP + phosphate + S-(2,4-dinitrophenyl)glutathione[side 2] | - |
? | |
| 7.6.2.3 | ATP + H2O + S-(cyanidin-3-glucosidyl)glutathione[side 1] | highest activity | Arabidopsis thaliana | ADP + phosphate + S-(cyanidin-3-glucosidyl)glutathione[side 2] | - |
? | |
| 7.6.2.3 | ATP + H2O + S-(metolachlor)glutathione[side 1] | - |
Arabidopsis thaliana | ADP + phosphate + S-(metolachlor)glutathione[side 2] | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 7.6.2.3 | glutathione S-conjugate pump | - |
Arabidopsis thaliana |
| 7.6.2.3 | MRP1 | - |
Arabidopsis thaliana |
| 7.6.2.3 | multidrug resistance-associated protein 1 | - |
Arabidopsis thaliana |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 7.6.2.3 | metabolism | the enzyme transports glutathione S-conjugates of xenobiotics and endogenous substances, including herbicides and anthocyanins out of the cytosol | Arabidopsis thaliana |
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Release 2023.1 (January 2023)
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