BRENDA - Enzyme Database

The diagnostic value and functional roles of phosphoglycerate mutase 1 in glioma

Xu, Z.; Gong, J.; Wang, C.; Wang, Y.; Song, Y.; Xu, W.; Liu, Z.; Liu, Y.; Oncol. Rep. 36, 2236-2244 (2016)

Data extracted from this reference:

Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
5.4.2.11
2-phospho-D-glycerate
Homo sapiens
-
3-phospho-D-glycerate
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
5.4.2.11
Homo sapiens
P18669
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
5.4.2.11
brain
-
Homo sapiens
-
5.4.2.11
glioma cell
-
Homo sapiens
-
5.4.2.11
U-87 cell
-
Homo sapiens
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.4.2.11
2-phospho-D-glycerate
-
748795
Homo sapiens
3-phospho-D-glycerate
-
-
-
?
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
5.4.2.11
2-phospho-D-glycerate
Homo sapiens
-
3-phospho-D-glycerate
-
-
?
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
5.4.2.11
brain
-
Homo sapiens
-
5.4.2.11
glioma cell
-
Homo sapiens
-
5.4.2.11
U-87 cell
-
Homo sapiens
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.4.2.11
2-phospho-D-glycerate
-
748795
Homo sapiens
3-phospho-D-glycerate
-
-
-
?
Expression
EC Number
Organism
Commentary
Expression
5.4.2.11
Homo sapiens
the mRNA and protein expression of the enzyme is significantly greater in glioma than normal brain tissues
up
General Information
EC Number
General Information
Commentary
Organism
5.4.2.11
malfunction
enzyme knockdown significantly inhibits glioma cell proliferation, promotes glioma cell apoptosis, induces S phase cell cycle arrest and inhibits glioma cell migration and invasion in vitro
Homo sapiens
5.4.2.11
physiological function
the enzyme is associated with the grade of glioma and is involved in the biological behavior of glioma cells
Homo sapiens
General Information (protein specific)
EC Number
General Information
Commentary
Organism
5.4.2.11
malfunction
enzyme knockdown significantly inhibits glioma cell proliferation, promotes glioma cell apoptosis, induces S phase cell cycle arrest and inhibits glioma cell migration and invasion in vitro
Homo sapiens
5.4.2.11
physiological function
the enzyme is associated with the grade of glioma and is involved in the biological behavior of glioma cells
Homo sapiens
Expression (protein specific)
EC Number
Organism
Commentary
Expression
5.4.2.11
Homo sapiens
the mRNA and protein expression of the enzyme is significantly greater in glioma than normal brain tissues
up