BRENDA - Enzyme Database

Indole alkaloids from tropical sponge Hyrtios sp. as isocitrate lyase inhibitors

Park, S.; Lee, Y.; Won, H.; Oh, K.; Lee, H.; Nat. Prod. Commun. 13, 683-685 (2018)
No PubMed abstract available

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
4.1.3.1
3,4-dihydrohyrtiosulawesine
-
Candida albicans
4.1.3.1
beta-ketoserotonin
-
Candida albicans
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
4.1.3.1
isocitrate
Candida albicans
-
succinate + glyoxylate
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
4.1.3.1
Candida albicans
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.1.3.1
isocitrate
-
748756
Candida albicans
succinate + glyoxylate
-
-
-
?
IC50 Value
EC Number
IC50 Value
IC50 Value Maximum
Commentary
Organism
Inhibitor
Structure
4.1.3.1
0.0929
-
pH and temperature not specified in the publication
Candida albicans
3,4-dihydrohyrtiosulawesine
IC50 Value (protein specific)
EC Number
IC50 Value
IC50 Value Maximum
Commentary
Organism
Inhibitor
Structure
4.1.3.1
0.0929
-
pH and temperature not specified in the publication
Candida albicans
3,4-dihydrohyrtiosulawesine
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
4.1.3.1
3,4-dihydrohyrtiosulawesine
-
Candida albicans
4.1.3.1
beta-ketoserotonin
-
Candida albicans
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
4.1.3.1
isocitrate
Candida albicans
-
succinate + glyoxylate
-
-
?
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.1.3.1
isocitrate
-
748756
Candida albicans
succinate + glyoxylate
-
-
-
?