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Literature summary extracted from

  • Oslund, R.C.; Su, X.; Haugbro, M.; Kee, J.M.; Esposito, M.; David, Y.; Wang, B.; Ge, E.; Perlman, D.H.; Kang, Y.; Muir, T.W.; Rabinowitz, J.D.
    Bisphosphoglycerate mutase controls serine pathway flux via 3-phosphoglycerate (2017), Nat. Chem. Biol., 13, 1081-1087 .
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.4.2.4 3-phospho-D-glyceroyl phosphate Homo sapiens
-
 2,3-bisphospho-D-glycerate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
5.4.2.4 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
5.4.2.4 4T1 cell
-
 Homo sapiens
-
5.4.2.4 A-431 cell
-
 Homo sapiens
-
5.4.2.4 HEK-293T cell
-
 Homo sapiens
-
5.4.2.4 HeLa cell
-
 Homo sapiens
-
5.4.2.4 U2-OS cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.4.2.4 3-phospho-D-glyceroyl phosphate
-
 Homo sapiens 2,3-bisphospho-D-glycerate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
5.4.2.4 BPGM
-
 Homo sapiens

General Information

EC Number General Information Comment Organism
5.4.2.4 malfunction enzyme deletion disrupts PGAM1 activity and results in higher serine de novo synthesis flux Homo sapiens
5.4.2.4 metabolism the enzyme primarily impacts 3-phosphoglycerate concentration and thereby serine pathway flux Homo sapiens