EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
5.4.2.11 | 2,6-dichloro-N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)benzenesulfonamide | - |
Homo sapiens | |
5.4.2.11 | 3-chloro-N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)-2-fluorobenzenesulfonamide | - |
Homo sapiens | |
5.4.2.11 | 4-(tert-butyl)-N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)benzenesulfonamide | - |
Homo sapiens | |
5.4.2.11 | 4-chloro-N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)benzenesulfonamide | - |
Homo sapiens | |
5.4.2.11 | 4-cyclohexyl-N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)benzenesulfonamide | - |
Homo sapiens | |
5.4.2.11 | 6-([1,1'-biphenyl]-4-sulfonamido)-8-hydroxy-9-oxo-9H-xanthen-2-yl acetate | - |
Homo sapiens | |
5.4.2.11 | epigallocatechin gallate | - |
Homo sapiens | |
5.4.2.11 | gemcitabine | - |
Homo sapiens | |
5.4.2.11 | MJE3 | - |
Homo sapiens | |
5.4.2.11 | N-(1,7-dihydroxy-9-oxo-9H-xanthen-3-yl)-[1,1'-biphenyl]-4-sulfonamide | - |
Homo sapiens | |
5.4.2.11 | N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)-1-phenylmethanesulfonamide | - |
Homo sapiens | |
5.4.2.11 | N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)-2-fluorobenzenesulfonamide | - |
Homo sapiens | |
5.4.2.11 | N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)-3,5-difluorobenzenesulfonamide | - |
Homo sapiens | |
5.4.2.11 | N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)-4-fluorobenzenesulfonamide | - |
Homo sapiens | |
5.4.2.11 | N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)-4-iodobenzenesulfonamide | - |
Homo sapiens | |
5.4.2.11 | N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)-4-methylbenzenesulfonamide | - |
Homo sapiens | |
5.4.2.11 | N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)-[1,1'-biphenyl]-4-sulfonamide | - |
Homo sapiens | |
5.4.2.11 | N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)benzenesulfonamide | - |
Homo sapiens | |
5.4.2.11 | N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)naphthalene-1-sulfonamide | - |
Homo sapiens | |
5.4.2.11 | N-(1-hydroxy-5-methoxy-9-oxo-9H-xanthen-3-yl)-[1,1'-biphenyl]-4-sulfonamide | - |
Homo sapiens | |
5.4.2.11 | N-(1-hydroxy-5-methyl-9-oxo-9H-xanthen-3-yl)-[1,1'-biphenyl]-4-sulfonamide | - |
Homo sapiens | |
5.4.2.11 | N-(1-hydroxy-7-methoxy-9-oxo-9H-xanthen-3-yl)-[1,1'-biphenyl]-4-sulfonamide | - |
Homo sapiens | |
5.4.2.11 | N-(1-hydroxy-7-methyl-9-oxo-9H-xanthen-3-yl)-[1,1'-biphenyl]-4-sulfonamide | - |
Homo sapiens | |
5.4.2.11 | N-(1-hydroxy-7-nitro-9-oxo-9H-xanthen-3-yl)-[1,1'-biphenyl]-4-sulfonamide | - |
Homo sapiens | |
5.4.2.11 | N-(1-hydroxy-9-oxo-9H-xanthen-3-yl)-[1,1'-biphenyl]-4-sulfonamide | - |
Homo sapiens | |
5.4.2.11 | N-(7-chloro-1-hydroxy-9-oxo-9H-xanthen-3-yl)-[1,1'-biphenyl]-4-sulfonamide | - |
Homo sapiens | |
5.4.2.11 | N-(7-fluoro-1-hydroxy-9-oxo-9H-xanthen-3-yl)-[1,1'-biphenyl]-4-sulfonamide | - |
Homo sapiens | |
5.4.2.11 | PGMI-004A | - |
Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
5.4.2.11 | 2-phospho-D-glycerate | Homo sapiens | - |
3-phospho-D-glycerate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
5.4.2.11 | Homo sapiens | P18669 | - |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
5.4.2.11 | 2-phospho-D-glycerate | - |
Homo sapiens | 3-phospho-D-glycerate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
5.4.2.11 | PGAM1 | - |
Homo sapiens |
5.4.2.11 | phosphoglycerate mutase 1 | - |
Homo sapiens |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
5.4.2.11 | 0.000193 | - |
at pH 8.0 and 25°C | Homo sapiens | gemcitabine | |
5.4.2.11 | 0.00049 | - |
at pH 8.0 and 25°C | Homo sapiens | epigallocatechin gallate | |
5.4.2.11 | 0.0021 | - |
at pH 8.0 and 25°C | Homo sapiens | N-(1-hydroxy-7-nitro-9-oxo-9H-xanthen-3-yl)-[1,1'-biphenyl]-4-sulfonamide | |
5.4.2.11 | 0.0027 | - |
at pH 8.0 and 25°C | Homo sapiens | 6-([1,1'-biphenyl]-4-sulfonamido)-8-hydroxy-9-oxo-9H-xanthen-2-yl acetate | |
5.4.2.11 | 0.0035 | - |
at pH 8.0 and 25°C | Homo sapiens | N-(7-chloro-1-hydroxy-9-oxo-9H-xanthen-3-yl)-[1,1'-biphenyl]-4-sulfonamide | |
5.4.2.11 | 0.0046 | - |
at pH 8.0 and 25°C | Homo sapiens | N-(1-hydroxy-7-methoxy-9-oxo-9H-xanthen-3-yl)-[1,1'-biphenyl]-4-sulfonamide | |
5.4.2.11 | 0.0055 | - |
at pH 8.0 and 25°C | Homo sapiens | N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)-[1,1'-biphenyl]-4-sulfonamide | |
5.4.2.11 | 0.0059 | - |
at pH 8.0 and 25°C | Homo sapiens | 4-cyclohexyl-N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)benzenesulfonamide | |
5.4.2.11 | 0.006 | - |
at pH 8.0 and 25°C | Homo sapiens | N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)naphthalene-1-sulfonamide | |
5.4.2.11 | 0.0064 | - |
at pH 8.0 and 25°C | Homo sapiens | 3-chloro-N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)-2-fluorobenzenesulfonamide | |
5.4.2.11 | 0.0064 | - |
at pH 8.0 and 25°C | Homo sapiens | N-(1,7-dihydroxy-9-oxo-9H-xanthen-3-yl)-[1,1'-biphenyl]-4-sulfonamide | |
5.4.2.11 | 0.0065 | - |
at pH 8.0 and 25°C | Homo sapiens | N-(1-hydroxy-5-methoxy-9-oxo-9H-xanthen-3-yl)-[1,1'-biphenyl]-4-sulfonamide | |
5.4.2.11 | 0.008 | - |
at pH 8.0 and 25°C | Homo sapiens | N-(1-hydroxy-7-methyl-9-oxo-9H-xanthen-3-yl)-[1,1'-biphenyl]-4-sulfonamide | |
5.4.2.11 | 0.0084 | - |
at pH 8.0 and 25°C | Homo sapiens | 4-(tert-butyl)-N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)benzenesulfonamide | |
5.4.2.11 | 0.0086 | - |
at pH 8.0 and 25°C | Homo sapiens | N-(1-hydroxy-5-methyl-9-oxo-9H-xanthen-3-yl)-[1,1'-biphenyl]-4-sulfonamide | |
5.4.2.11 | 0.0101 | - |
at pH 8.0 and 25°C | Homo sapiens | N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)-4-iodobenzenesulfonamide | |
5.4.2.11 | 0.0102 | - |
at pH 8.0 and 25°C | Homo sapiens | 2,6-dichloro-N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)benzenesulfonamide | |
5.4.2.11 | 0.0131 | - |
at pH 8.0 and 25°C | Homo sapiens | PGMI-004A | |
5.4.2.11 | 0.0132 | - |
at pH 8.0 and 25°C | Homo sapiens | N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)-3,5-difluorobenzenesulfonamide | |
5.4.2.11 | 0.0137 | - |
at pH 8.0 and 25°C | Homo sapiens | N-(7-fluoro-1-hydroxy-9-oxo-9H-xanthen-3-yl)-[1,1'-biphenyl]-4-sulfonamide | |
5.4.2.11 | 0.0143 | - |
at pH 8.0 and 25°C | Homo sapiens | N-(1-hydroxy-9-oxo-9H-xanthen-3-yl)-[1,1'-biphenyl]-4-sulfonamide | |
5.4.2.11 | 0.02 | - |
at pH 8.0 and 25°C | Homo sapiens | N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)-4-methylbenzenesulfonamide | |
5.4.2.11 | 0.02 | - |
IC50 value above 0.02 mM, at pH 8.0 and 25°C | Homo sapiens | 4-chloro-N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)benzenesulfonamide | |
5.4.2.11 | 0.02 | - |
IC50 value above 0.02 mM, at pH 8.0 and 25°C | Homo sapiens | N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)-1-phenylmethanesulfonamide | |
5.4.2.11 | 0.02 | - |
IC50 value above 0.02 mM, at pH 8.0 and 25°C | Homo sapiens | N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)-2-fluorobenzenesulfonamide | |
5.4.2.11 | 0.02 | - |
IC50 value above 0.02 mM, at pH 8.0 and 25°C | Homo sapiens | N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)-4-fluorobenzenesulfonamide | |
5.4.2.11 | 0.02 | - |
IC50 value above 0.02 mM, at pH 8.0 and 25°C | Homo sapiens | N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)benzenesulfonamide | |
5.4.2.11 | 0.033 | - |
at pH 8.0 and 25°C | Homo sapiens | MJE3 |