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Literature summary extracted from

  • Tuan, P.A.; Zhao, S.; Kim, J.K.; Kim, Y.B.; Yang, J.; Li, C.H.; Kim, S.J.; Arasu, M.V.; Al-Dhabi, N.A.; Park, S.U.
    Riboflavin accumulation and molecular characterization of cDNAs encoding bifunctional GTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase, lumazine synthase, and riboflavin synthase in different organs of Lycium chinense plant (2014), Molecules, 19, 17141-17153 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.1.99.12 LcRIBA, sequence comparisons, quantitative real-time PCR expression analysis Lycium chinense

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.99.12 D-ribulose 5-phosphate Lycium chinense
-
 formate + L-3,4-dihydroxybutan-2-one 4-phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.1.99.12 Lycium chinense W0FER2 cv. Cheongmyeong
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.1.99.12 flower
-
 Lycium chinense
-
4.1.99.12 fruit green and red Lycium chinense
-
4.1.99.12 leaf highest enzyme expression level Lycium chinense
-
4.1.99.12 additional information real-time PCR expression analysis in different organs of the plant, transcription of LcRIBA is the highest in the leaves, moderate in the roots, stem, and flowers, and weak in the green and red fruits Lycium chinense
-
4.1.99.12 root
-
 Lycium chinense
-
4.1.99.12 stem
-
 Lycium chinense
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.99.12 D-ribulose 5-phosphate
-
 Lycium chinense formate + L-3,4-dihydroxybutan-2-one 4-phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.1.99.12 bifunctional GCHYII/DHBP
-
 Lycium chinense
4.1.99.12 bifunctional GTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase
-
 Lycium chinense
4.1.99.12 LcRIBA
-
 Lycium chinense

General Information

EC Number General Information Comment Organism
4.1.99.12 metabolism the bifunctional GTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase (LcRIBA) catalyzes 2 initial reactions in riboflavin biosynthetic pathway Lycium chinense