Literature summary extracted from

Okugawa, S.; Moayeri, M.; Pomerantsev, A.; Sastalla, I.; Crown, D.; Gupta, P.; Leppla, S.
Lipoprotein biosynthesis by prolipoprotein diacylglyceryl transferase is required for efficient spore germination and full virulence of Bacillus anthracis (2012), Mol. Microbiol., 83, 96-109 .

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
2.5.1.145	L-1-phosphatidyl-sn-glycerol + a [prolipoprotein]-L-cysteine	Bacillus anthracis	-	sn-glycerol 1-phosphate + an [prolipoprotein]-S-1,2-diacyl-sn-glyceryl-L-cysteine	-	?
2.5.1.145	L-1-phosphatidyl-sn-glycerol + a [prolipoprotein]-L-cysteine	Bacillus anthracis Ames 35	-	sn-glycerol 1-phosphate + an [prolipoprotein]-S-1,2-diacyl-sn-glyceryl-L-cysteine	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.5.1.145	Bacillus anthracis	-	-	-
2.5.1.145	Bacillus anthracis Ames 35	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.5.1.145	L-1-phosphatidyl-sn-glycerol + a [prolipoprotein]-L-cysteine	-	Bacillus anthracis	sn-glycerol 1-phosphate + an [prolipoprotein]-S-1,2-diacyl-sn-glyceryl-L-cysteine	-	?
2.5.1.145	L-1-phosphatidyl-sn-glycerol + a [prolipoprotein]-L-cysteine	-	Bacillus anthracis Ames 35	sn-glycerol 1-phosphate + an [prolipoprotein]-S-1,2-diacyl-sn-glyceryl-L-cysteine	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
2.5.1.145	LGT	-	Bacillus anthracis
2.5.1.145	prolipoprotein diacylglyceryl transferase	-	Bacillus anthracis

General Information

EC Number	General Information	Comment	Organism
2.5.1.145	physiological function	the enzyme is required for efficient spore germination and full virulence of Bacillus anthracis	Bacillus anthracis

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Release 2023.1 (January 2023)