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Literature summary extracted from

  • Holden, K.M.; Gilbert, M.; Coloe, P.J.; Li, J.; Fry, B.N.
    The role of WlaRG, WlaTB and WlaTC in lipooligosaccharide synthesis by Campylobacter jejuni strain 81116 (2012), Microb. Pathog., 52, 344-352 .
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.6.1.B19 dTDP-3-dehydro-6-deoxy-D-glucose + D-glutamate Campylobacter jejuni 81116 the enzyme is involved in lipooligosaccharide synthesis. Campylobacter jejuni produces a range of glycans including lipooligosaccharide, an important virulence factor dTDP-3-amino-3,6-dideoxy-D-glucose + 2-oxoglutarate
-
?
2.6.1.B19 dTDP-3-dehydro-6-deoxy-galactose + D-glutamate Campylobacter jejuni 81116 the enzyme is involved in lipooligosaccharide synthesis. Campylobacter jejuni produces a range of glycans including lipooligosaccharide, an important virulence factor dTDP-3-amino-3,6-dideoxy-D-galactose + 2-oxoglutarate
-
?

Organism

EC Number Organism UniProt Comment Textmining
2.6.1.B19 Campylobacter jejuni 81116
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-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.6.1.B19 dTDP-3-dehydro-6-deoxy-D-glucose + D-glutamate
-
Campylobacter jejuni 81116 dTDP-3-amino-3,6-dideoxy-D-glucose + 2-oxoglutarate
-
?
2.6.1.B19 dTDP-3-dehydro-6-deoxy-D-glucose + D-glutamate the enzyme is involved in lipooligosaccharide synthesis. Campylobacter jejuni produces a range of glycans including lipooligosaccharide, an important virulence factor Campylobacter jejuni 81116 dTDP-3-amino-3,6-dideoxy-D-glucose + 2-oxoglutarate
-
?
2.6.1.B19 dTDP-3-dehydro-6-deoxy-galactose + D-glutamate
-
Campylobacter jejuni 81116 dTDP-3-amino-3,6-dideoxy-D-galactose + 2-oxoglutarate
-
?
2.6.1.B19 dTDP-3-dehydro-6-deoxy-galactose + D-glutamate the enzyme is involved in lipooligosaccharide synthesis. Campylobacter jejuni produces a range of glycans including lipooligosaccharide, an important virulence factor Campylobacter jejuni 81116 dTDP-3-amino-3,6-dideoxy-D-galactose + 2-oxoglutarate
-
?

Synonyms

EC Number Synonyms Comment Organism
2.6.1.B19 WlaRG
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Campylobacter jejuni 81116

General Information

EC Number General Information Comment Organism
2.6.1.B19 malfunction the wlaRG mutant is non-motile and aflagellate. The wlaRG mutant displays reduced adherence to chicken embryo fibroblasts. The mutant strain is less invasive of human cells than the wild-type strain Campylobacter jejuni 81116
2.6.1.B19 metabolism the enzyme is involved in lipooligosaccharide synthesis. Campylobacter jejuni produces a range of glycans including lipooligosaccharide, an important virulence factor Campylobacter jejuni 81116
2.6.1.B19 physiological function the enzyme is involved in lipooligosaccharide synthesis. Campylobacter jejuni produces a range of glycans including lipooligosaccharide, an important virulence factor Campylobacter jejuni 81116