EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
4.2.1.10 | 3-[(Z)-[(5Z)-3-ethyl-5-[[4-(2-methoxy-2-oxoethoxy)phenyl]methylidene]-4-oxo-1,3-thiazolidin-2-ylidene]amino]benzoic acid | no cytotoxicity up to 100 microM | Mycobacterium tuberculosis | |
4.2.1.10 | 3-[(Z)-[(5Z)-5-[[4-(benzyloxy)phenyl]methylidene]-3-methyl-4-oxo-1,3-thiazolidin-2-ylidene]amino]benzoic acid | no cytotoxicity up to 100 microM | Mycobacterium tuberculosis |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.2.1.10 | Mycobacterium tuberculosis | P9WPX7 | - |
- |
4.2.1.10 | Mycobacterium tuberculosis H37Rv | P9WPX7 | - |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.2.1.10 | 3-dehydroquinate | - |
Mycobacterium tuberculosis | 3-dehydroshikimate + H2O | - |
? | |
4.2.1.10 | 3-dehydroquinate | - |
Mycobacterium tuberculosis H37Rv | 3-dehydroshikimate + H2O | - |
? |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
4.2.1.10 | 0.0171 | - |
pH 7.0, 25°C | Mycobacterium tuberculosis | 3-[(Z)-[(5Z)-3-ethyl-5-[[4-(2-methoxy-2-oxoethoxy)phenyl]methylidene]-4-oxo-1,3-thiazolidin-2-ylidene]amino]benzoic acid | |
4.2.1.10 | 0.0315 | - |
pH 7.0, 25°C | Mycobacterium tuberculosis | 3-[(Z)-[(5Z)-5-[[4-(benzyloxy)phenyl]methylidene]-3-methyl-4-oxo-1,3-thiazolidin-2-ylidene]amino]benzoic acid |