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Literature summary extracted from

  • Bjornsdottir-Butler, K.; Bencsath, F.A.; McCarthy, S.; Benner, R.A.
    Heat resistance of histidine decarboxylase from Gram-negative histamine-producing bacteria in seafood (2017), J. Food Prot., 80, 1273-1279 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.1.1.22 gene hdc, recombinant expression of His-tagged enzyme in Escherichia coli Morganella morganii
4.1.1.22 gene hdc, recombinant expression of His-tagged enzyme in Escherichia coli Raoultella planticola
4.1.1.22 gene hdc, recombinant expression of His-tagged enzyme in Escherichia coli Klebsiella aerogenes
4.1.1.22 gene hdc, recombinant expression of His-tagged enzyme in Escherichia coli Photobacterium damselae subsp. damselae

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.1.22 L-histidine Morganella morganii
-
histamine + CO2
-
?
4.1.1.22 L-histidine Raoultella planticola
-
histamine + CO2
-
?
4.1.1.22 L-histidine Klebsiella aerogenes
-
histamine + CO2
-
?
4.1.1.22 L-histidine Photobacterium damselae subsp. damselae
-
histamine + CO2
-
?

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.22 Klebsiella aerogenes P28577 i.e. Klebsiella aerogenes
-
4.1.1.22 Morganella morganii P05034 i.e. Proteus morganii
-
4.1.1.22 Photobacterium damselae subsp. damselae A0A1X9TYE5 i.e. Listonella damsela
-
4.1.1.22 Raoultella planticola P28578 i.e. Klebsiella planticola
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.1.1.22 recombinant His-tagged enzyme from Escherichia coli by cobalt affinity chromatography Morganella morganii
4.1.1.22 recombinant His-tagged enzyme from Escherichia coli by cobalt affinity chromatography Raoultella planticola
4.1.1.22 recombinant His-tagged enzyme from Escherichia coli by cobalt affinity chromatography Klebsiella aerogenes
4.1.1.22 recombinant His-tagged enzyme from Escherichia coli by cobalt affinity chromatography Photobacterium damselae subsp. damselae

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.22 L-histidine
-
Morganella morganii histamine + CO2
-
?
4.1.1.22 L-histidine
-
Raoultella planticola histamine + CO2
-
?
4.1.1.22 L-histidine
-
Klebsiella aerogenes histamine + CO2
-
?
4.1.1.22 L-histidine
-
Photobacterium damselae subsp. damselae histamine + CO2
-
?

Synonyms

EC Number Synonyms Comment Organism
4.1.1.22 HDC
-
Morganella morganii
4.1.1.22 HDC
-
Raoultella planticola
4.1.1.22 HDC
-
Klebsiella aerogenes
4.1.1.22 HDC
-
Photobacterium damselae subsp. damselae

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
4.1.1.22 50 60 heat resistance analysis of the enzyme at 50-100°C, and determination of D-value 1.6-2.9 and z-value 13.3 for the Photobacterium damselae strain, isolated from tuna, at 50-65°C. The enzyme is inactivated at 60°C Photobacterium damselae subsp. damselae
4.1.1.22 50 60 heat resistance analysis of the enzyme at 50-100°C, and determination of D-value 1.6-4.1 and z-value 19.2 for the Morganella morganii strain, isolated from tuna, at 50-65°C. The enzyme is inactivated at 60°C Morganella morganii
4.1.1.22 50 60 heat resistance analysis of the enzyme at 50-100°C, and determination of D-value 1.6-6.3 and z-value 18.0 for the Enterobacter aerogenes strain, isolated from tuna, at 50-65°C. The enzyme is inactivated at 60°C Klebsiella aerogenes
4.1.1.22 50 60 heat resistance analysis of the enzyme at 50-100°C, and determination of D-value 1.9-4.3 and z-value 22.0 for the Raoultella planticola strain, isolated from tuna, at 50-65°C. The enzyme is inactivated at 60°C Raoultella planticola