Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Lin, L.; Gopal, S.; Sharda, A.; Passam, F.; Bowley, S.R.; Stopa, J.; Xue, G.; Yuan, C.; Furie, B.C.; Flaumenhaft, R.; Huang, M.; Furie, B.
    Quercetin-3-rutinoside inhibits protein disulfide isomerase by binding to its b'x domain (2015), J. Biol. Chem., 290, 23543-23552 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
5.3.4.1 expressed in Escherichia coli Origami B (DE3) cells Mus musculus

Inhibitors

EC Number Inhibitors Comment Organism Structure
5.3.4.1 isoquercetin
-
 Mus musculus
5.3.4.1 quercetin-3-rutinoside
-
 Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
5.3.4.1 Mus musculus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
5.3.4.1 complete His-Tag purification resin column chromatography and Superdex 200 gel filtration Mus musculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Synonyms

EC Number Synonyms Comment Organism
5.3.4.1 ERp5
-
 Mus musculus
5.3.4.1 ERp57
-
 Mus musculus
5.3.4.1 ERp72
-
 Mus musculus
5.3.4.1 PDI
-
 Mus musculus
5.3.4.1 protein disulfide isomerase
-
 Mus musculus

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
5.3.4.1 0.0123
-
 at pH 7.4 and 25°C Mus musculus quercetin-3-rutinoside
5.3.4.1 0.014
-
 at pH 7.4 and 25°C Mus musculus isoquercetin