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Literature summary extracted from

  • Elhaik Goldman, S.; Dotan, S.; Talias, A.; Lilo, A.; Azriel, S.; Malka, I.; Portnoi, M.; Ohayon, A.; Kafka, D.; Ellis, R.; Elkabets, M.; Porgador, A.; Levin, D.; Azhari, R.; Swiatlo, E.; Ling, E.; Feldman, G.; Tal, M.; Dagan, R.; Mizrachi Nebenzahl, Y.
    Streptococcus pneumoniae fructose-1,6-bisphosphate aldolase, a protein vaccine candidate, elicits Th1/Th2/Th17-type cytokine responses in mice (2016), Int. J. Mol. Med., 37, 1127-1138 .
    View publication on PubMed

Application

EC Number Application Comment Organism
4.1.2.13 drug development Streptococcus pneumoniae fructose-1,6-bisphosphate aldolase is a protein vaccine candidate, elicits Th1/Th2/Th17-type cytokine responses in mice Streptococcus pneumoniae serotype 3

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.1.2.13
-
Streptococcus pneumoniae serotype 3
4.1.2.13 expressed in Escherichia coli BL21(DE3) cells Streptococcus pneumoniae

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
4.1.2.13 cell surface
-
Streptococcus pneumoniae 9986
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.2.13 D-fructose 1,6-bisphosphate Streptococcus pneumoniae
-
glycerone phosphate + D-glyceraldehyde 3-phosphate
-
?
4.1.2.13 D-fructose 1,6-bisphosphate Streptococcus pneumoniae WU2
-
glycerone phosphate + D-glyceraldehyde 3-phosphate
-
?

Organism

EC Number Organism UniProt Comment Textmining
4.1.2.13 Streptococcus pneumoniae
-
serotype 3
-
4.1.2.13 Streptococcus pneumoniae serotype 3
-
-
-
4.1.2.13 Streptococcus pneumoniae serotype 3 WU2
-
-
-
4.1.2.13 Streptococcus pneumoniae WU2
-
serotype 3
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.1.2.13
-
Streptococcus pneumoniae serotype 3
4.1.2.13 anion-exchange column chromatography and gel filtration Streptococcus pneumoniae

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.2.13 D-fructose 1,6-bisphosphate
-
Streptococcus pneumoniae glycerone phosphate + D-glyceraldehyde 3-phosphate
-
?
4.1.2.13 D-fructose 1,6-bisphosphate
-
Streptococcus pneumoniae WU2 glycerone phosphate + D-glyceraldehyde 3-phosphate
-
?

Synonyms

EC Number Synonyms Comment Organism
4.1.2.13 FBA
-
Streptococcus pneumoniae
4.1.2.13 fructose-1,6-bisphosphate aldolase
-
Streptococcus pneumoniae
4.1.2.13 fructose-1,6-bisphosphate aldolase
-
Streptococcus pneumoniae serotype 3