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Literature summary extracted from

  • Van Luyn, M.; Muller, M.; Renes, J.; Meijer, C.; Scheper, R.; Nienhuis, E.; Mulder, N.; Jansen, P.; De Vries, E.
    Transport of glutathione conjugates into secretory vesicles is mediated by the multidrug-resistance protein 1 (1998), Int. J. Cancer, 76, 55-62 .
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
7.6.2.3 Golgi apparatus
-
 Homo sapiens 5794
-
7.6.2.3 plasma membrane
-
 Homo sapiens 5886
-
7.6.2.3 vesicular membrane
-
 Homo sapiens
-
-

Organism

EC Number Organism UniProt Comment Textmining
7.6.2.3 Homo sapiens P33527
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
7.6.2.3 GLC-4 cell
-
 Homo sapiens
-
7.6.2.3 GLC-4/ADR cell
-
 Homo sapiens
-
7.6.2.3 small cell lung carcinoma cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.6.2.3 ATP + H2O + 5-chloro-methyl fluorescein diacetate[side 1]
-
 Homo sapiens ADP + phosphate + 5-chloro-methyl fluorescein diacetate[side 2]
-
 ?
7.6.2.3 ATP + H2O + monochlorobimane[side 1]
-
 Homo sapiens ADP + phosphate + monochlorobimane[side 2]
-
 ?
7.6.2.3 ATP + H2O + S-(1-chloro-2,4-dinitrobenzyl)-glutathione[side 1]
-
 Homo sapiens ADP + phosphate + S-(1-chloro-2,4-dinitrobenzyl)-glutathione[side 2]
-
 ?

Synonyms

EC Number Synonyms Comment Organism
7.6.2.3 MRP1
-
 Homo sapiens
7.6.2.3 multidrug-resistance protein 1
-
 Homo sapiens