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Literature summary extracted from

  • Ali Khan, H.; Mutus, B.
    Protein disulfide isomerase a multifunctional protein with multiple physiological roles (2014), Front. Chem., 2, 70 .
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
5.3.4.1 bacitracin
-
 Homo sapiens
5.3.4.1 ethyl N-[[[(cyanocarbonyl)(2,4-dimethoxyphenyl)amino]thiophen-2-yl]acetyl]glycinate
-
 Homo sapiens
5.3.4.1 phenyl vinyl sulfonate
-
 Homo sapiens
5.3.4.1 quercetin 3-rutinoside
-
 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
5.3.4.1 cell surface
-
 Homo sapiens 9986
-
5.3.4.1 cytosol
-
 Homo sapiens 5829
-
5.3.4.1 endoplasmic reticulum
-
 Homo sapiens 5783
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.3.4.1 beta-actin Homo sapiens
-
 ?
-
 ?
5.3.4.1 additional information Homo sapiens the enzyme has three catalytic activities including thiol-disulfide oxireductase, disulfide isomerase, and redox-dependent chaperone ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
5.3.4.1 Homo sapiens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.3.4.1 beta-actin
-
 Homo sapiens ?
-
 ?
5.3.4.1 additional information the enzyme has three catalytic activities including thiol-disulfide oxireductase, disulfide isomerase, and redox-dependent chaperone Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
5.3.4.1 PDI
-
 Homo sapiens
5.3.4.1 protein disulfide isomerase
-
 Homo sapiens