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Literature summary extracted from

  • Prabhudesai, S.; Koceja, C.; Dey, A.; Eisa-Beygi, S.; Leigh, N.; Bhattacharya, R.; Mukherjee, P.; Ramchandran, R.
    Cystathionine beta-synthase is necessary for axis development in vivo (2018), Front. Cell Dev. Biol., 6, 14 .
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
4.2.1.22 Danio rerio
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.2.1.22 embryo wide expression pattern for isoforms Cbsa and Cbsb primarily along the embryonic axis of the developing embryo Danio rerio
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General Information

EC Number General Information Comment Organism
4.2.1.22 physiological function isoform Cbsb is responsible for anterior-posterior axis development, and Cbsa function is redundant. Cbsb loss of function fish embryos show shortened and bent axis, along with less H2S and more homocysteine Danio rerio