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Literature summary extracted from

  • Nishimura, A.; Kotani, T.; Sasano, Y.; Takagi, H.
    An antioxidative mechanism mediated by the yeast N-acetyltransferase Mpr1 Oxidative stress-induced arginine synthesis and its physiological role (2010), FEMS Yeast Res., 10, 687-698 .
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.271 mitochondrion
-
 Saccharomyces cerevisiae 5739
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.271 acetyl-CoA + DELTA1-pyrroline-5-carboxylate + H2O Saccharomyces cerevisiae
-
 CoA + N-acetyl-glutamate-gamma-semialdehyde
-
 ?
2.3.1.271 acetyl-CoA + DELTA1-pyrroline-5-carboxylate + H2O Saccharomyces cerevisiae Sigma1278b
-
 CoA + N-acetyl-glutamate-gamma-semialdehyde
-
 ?
2.3.1.271 acetyl-CoA + glutamate-gamma-semialdehyde Saccharomyces cerevisiae
-
 CoA + N-acetyl-glutamate-gamma-semialdehyde
-
 ?
2.3.1.271 acetyl-CoA + glutamate-gamma-semialdehyde Saccharomyces cerevisiae Sigma1278b
-
 CoA + N-acetyl-glutamate-gamma-semialdehyde
-
 ?
2.3.1.271 acetyl-CoA + L-azetidine-2-carboxylic acid Saccharomyces cerevisiae
-
 CoA + N-acetyl-L-azetidine-2-carboxylic acid
-
 ?
2.3.1.271 acetyl-CoA + L-azetidine-2-carboxylic acid Saccharomyces cerevisiae Sigma1278b
-
 CoA + N-acetyl-L-azetidine-2-carboxylic acid
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.271 Saccharomyces cerevisiae E9P8D2
-
-
2.3.1.271 Saccharomyces cerevisiae Sigma1278b E9P8D2
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.271 acetyl-CoA + DELTA1-pyrroline-5-carboxylate + H2O
-
 Saccharomyces cerevisiae CoA + N-acetyl-glutamate-gamma-semialdehyde
-
 ?
2.3.1.271 acetyl-CoA + DELTA1-pyrroline-5-carboxylate + H2O
-
 Saccharomyces cerevisiae Sigma1278b CoA + N-acetyl-glutamate-gamma-semialdehyde
-
 ?
2.3.1.271 acetyl-CoA + glutamate-gamma-semialdehyde
-
 Saccharomyces cerevisiae CoA + N-acetyl-glutamate-gamma-semialdehyde
-
 ?
2.3.1.271 acetyl-CoA + glutamate-gamma-semialdehyde
-
 Saccharomyces cerevisiae Sigma1278b CoA + N-acetyl-glutamate-gamma-semialdehyde
-
 ?
2.3.1.271 acetyl-CoA + L-azetidine-2-carboxylic acid
-
 Saccharomyces cerevisiae CoA + N-acetyl-L-azetidine-2-carboxylic acid
-
 ?
2.3.1.271 acetyl-CoA + L-azetidine-2-carboxylic acid
-
 Saccharomyces cerevisiae Sigma1278b CoA + N-acetyl-L-azetidine-2-carboxylic acid
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.271 MPR1
-
 Saccharomyces cerevisiae

General Information

EC Number General Information Comment Organism
2.3.1.271 metabolism the enzyme converts DELTA1-pyrroline-5-carboxylate/glutamate-gamma-semialdehyde into N-acetyl-glutamate-gamma-semialdehyde for arginine synthesis in the mitochondria, indicating that the enzyme mediates the proline and arginine metabolic pathways. Enzyme-dependent arginine synthesis confers stress tolerance Saccharomyces cerevisiae