Any feedback?
Literature summary extracted from
- Complete catalytic cycle of cofactor-independent phosphoglycerate mutase involves a spring-loaded mechanism (2015), FEBS J., 282, 1097-1110 .
Crystallization (Commentary)
| EC Number | Crystallization (Comment) | Organism |
|---|---|---|
| 5.4.2.12 | hanging drop vapor diffusion method, using 0.2 M NaCl, 0.1 M Bis/Tris pH 6.3 and 25% (w/v) polyethylene glycol 3350 | Staphylococcus aureus |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.4.2.12 | Mn2+ | dependent on | Staphylococcus aureus |  |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.4.2.12 | 2-phospho-D-glycerate | Staphylococcus aureus | - |
3-phospho-D-glycerate | - |
r | |
| 5.4.2.12 | 2-phospho-D-glycerate | Staphylococcus aureus NCTC 8325 | - |
3-phospho-D-glycerate | - |
r | |
| 5.4.2.12 | 3-phospho-D-glycerate | Staphylococcus aureus | - |
2-phospho-D-glycerate | - |
r | |
| 5.4.2.12 | 3-phospho-D-glycerate | Staphylococcus aureus NCTC 8325 | - |
2-phospho-D-glycerate | - |
r | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 5.4.2.12 | Staphylococcus aureus | Q2G029 | - |
- |
| 5.4.2.12 | Staphylococcus aureus NCTC 8325 | Q2G029 | - |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 5.4.2.12 | - |
Staphylococcus aureus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.4.2.12 | 2-phospho-D-glycerate | - |
Staphylococcus aureus | 3-phospho-D-glycerate | - |
r | |
| 5.4.2.12 | 2-phospho-D-glycerate | - |
Staphylococcus aureus NCTC 8325 | 3-phospho-D-glycerate | - |
r | |
| 5.4.2.12 | 3-phospho-D-glycerate | - |
Staphylococcus aureus | 2-phospho-D-glycerate | - |
r | |
| 5.4.2.12 | 3-phospho-D-glycerate | - |
Staphylococcus aureus NCTC 8325 | 2-phospho-D-glycerate | - |
r | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 5.4.2.12 | cofactor-independent phosphoglycerate mutase | - |
Staphylococcus aureus |
| 5.4.2.12 | iPGM | - |
Staphylococcus aureus |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.4.2.12 | additional information | the enzyme is independent from 2,3-bisphosphoglycerate | Staphylococcus aureus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
