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Literature summary extracted from

  • Li, D.; Howe, N.; Dukkipati, A.; Shah, S.T.; Bax, B.D.; Edge, C.; Bridges, A.; Hardwicke, P.; Singh, O.M.; Giblin, G.; Pautsch, A.; Pfau, R.; Schnapp, G.; Wang, M.; Olieric, V.; Caffrey, M.
    Crystallizing membrane proteins in the lipidic mesophase. Experience with human prostaglandin E2 synthase 1 and an evolving strategy (2014), Cryst. Growth Des., 14, 2034-2047 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
5.3.99.3 expressed in Spodoptera frugiperda Sf 9 cells Homo sapiens

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
5.3.99.3
-
 Homo sapiens

General Stability

EC Number General Stability Organism
5.3.99.3 reduced glutathione is essential to stabilize the enzyme Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
5.3.99.3 microsome
-
 Homo sapiens
-
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
5.3.99.3 126000
-
 gel filtration Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.3.99.3 Prostaglandin H2 Homo sapiens
-
 Prostaglandin E2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
5.3.99.3 Homo sapiens O14684
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
5.3.99.3 Ni-NTA resin column chromatography and Superdex 200 gel filtration Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.3.99.3 Prostaglandin H2
-
 Homo sapiens Prostaglandin E2
-
 ?

Subunits

EC Number Subunits Comment Organism
5.3.99.3 heptamer 7 * 18000, SDS-PAGE Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
5.3.99.3 microsomal prostaglandin E2 synthase 1
-
 Homo sapiens
5.3.99.3 MPGES1
-
 Homo sapiens