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Literature summary extracted from

  • Asif, M.; Bhalla, T.C.
    Enantiopure synthesis of (R)-mandelonitrile Using Hydroxynitrile lyase of wild apricot (Prunus armeniaca L.) [ParsHNL] in aqueous/organic biphasic system (2017), Catal. Lett., 147, 1592-1597 .
No PubMed abstract available

Application

EC Number Application Comment Organism
4.1.2.10 agriculture hydroxynitrile lyases are involved in the synthesis of enantiomerically pure cyanohydrins which are important intermediates in the production of pharmaceuticals and agrochemicals. The enzyme synthesizes (R)-mandelonitrile in both, batch reaction and fed-batch reaction and can be effectively used in the synthesis of (R)-mandelonitrile Prunus armeniaca
4.1.2.10 pharmacology hydroxynitrile lyases are involved in the synthesis of enantiomerically pure cyanohydrins which are important intermediates in the production of pharmaceuticals and agrochemicals. The enzyme synthesizes (R)-mandelonitrile in both, batch reaction and fed-batch reaction and can be effectively used in the synthesis of (R)-mandelonitrile Prunus armeniaca
4.1.2.10 synthesis hydroxynitrile lyases are involved in the synthesis of enantiomerically pure cyanohydrins which are important intermediates in the production of pharmaceuticals and agrochemicals. The enzyme synthesizes (R)-mandelonitrile in both, batch reaction and fed-batch reaction and can be effectively used in the synthesis of (R)-mandelonitrile Prunus armeniaca

Organism

EC Number Organism UniProt Comment Textmining
4.1.2.10 Prunus armeniaca
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.2.10 cyanide + benzaldehyde the enzyme catalyses synthesis of (R)-mandelonitrile in methyl-tbutyl ether/citrate buffer biphasic system with more than 99% enantiomeric excess Prunus armeniaca (R)-mandelonitrile
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 r

Synonyms

EC Number Synonyms Comment Organism
4.1.2.10 ParsHNL
-
 Prunus armeniaca

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
4.1.2.10 15
-
-
 Prunus armeniaca

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.1.2.10 4
-
-
 Prunus armeniaca