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Literature summary extracted from

  • Yamanashi, T.; Kim, S.Y.; Hara, H.; Funa, N.
    In vitro reconstitution of the catabolic reactions catalyzed by PcaHG, PcaB, and PcaL the protocatechuate branch of the beta-ketoadipate pathway in Rhodococcus jostii RHA1 (2015), Biosci. Biotechnol. Biochem., 79, 830-835 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.1.1.24 expression in Escherichia coli Rhodococcus jostii
4.1.1.44 expression in Escherichia coli Rhodococcus jostii

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.24 3-oxoadipate enol-lactone + H2O Rhodococcus jostii
-
3-oxoadipate
-
?
3.1.1.24 additional information Rhodococcus jostii PcaL is a bidomain, bifunctional protein consisting of gamma-carboxy-muconolactone decarboxylase and 3-oxoadipate enol-lactone hydrolase activities ?
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.24 Rhodococcus jostii Q0SH24
-
-
3.1.1.24 Rhodococcus jostii Q0SH24 bifunctional 3-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone decarboxylase, EC 3.1.1.24 and EC 4.1.1.44, respectively
-
4.1.1.44 Rhodococcus jostii Q0SH24 bifunctional 3-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone decarboxylase, EC 3.1.1.24 and EC 4.1.1.44, respectively
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.24 3-oxoadipate enol-lactone + H2O
-
Rhodococcus jostii 3-oxoadipate
-
?
3.1.1.24 additional information enzyme additionally catalyzes the decarboxylation of 4-carboxymuconolactone to give substrate beta-oxoadipate enol-lactone, reaction of EC 4.1.1.44 Rhodococcus jostii ?
-
?
3.1.1.24 additional information PcaL is a bidomain, bifunctional protein consisting of gamma-carboxy-muconolactone decarboxylase and 3-oxoadipate enol-lactone hydrolase activities Rhodococcus jostii ?
-
?
3.1.1.24 additional information product identification by LC-MS and NMR spectrometric analysis Rhodococcus jostii ?
-
?
4.1.1.44 4-carboxymuconolactone
-
Rhodococcus jostii beta-oxoadipate enol-lactone + CO2
-
?
4.1.1.44 additional information enzyme additionally catalyzes the conversion of product beta-oxoadipate enol-lactone to beta-oxoadipate, reaction of EC 3.1.1.24 Rhodococcus jostii ?
-
?

Subunits

EC Number Subunits Comment Organism
3.1.1.24 ? x * 40000, SDS-PAGE Rhodococcus jostii

Synonyms

EC Number Synonyms Comment Organism
3.1.1.24 3-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone decarboxylase EC 3.1.1.24 and EC 4.1.1.44, respectively Rhodococcus jostii
3.1.1.24 beta-ketoadipate enol-lactone hydrolase
-
Rhodococcus jostii
3.1.1.24 PcaL
-
Rhodococcus jostii
3.1.1.24 RHA1_ro01338 locus name Rhodococcus jostii
4.1.1.44 3-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone decarboxylase EC 3.1.1.24 and EC 4.1.1.44, respectively Rhodococcus jostii
4.1.1.44 PcaL
-
Rhodococcus jostii

General Information

EC Number General Information Comment Organism
3.1.1.24 metabolism the enzyme is involved in the protocatechuate branch of the 3-oxoadipate pathway, which is a major pathway involved in the catabolism of the aromatic compounds in microbes Rhodococcus jostii