BRENDA - Enzyme Database

Cofactor independent phosphoglycerate mutase of Brugia malayi induces a mixed Th1/Th2 type immune response and inhibits larval development in the host

Singh, P.; Kushwaha, S.; Rana, A.; Misra-Bhattacharya, S.; BioMed Res. Int. 2014, 590281 (2014)

Data extracted from this reference:

Cloned(Commentary)
EC Number
Commentary
Organism
5.4.2.12
expressed in Escherichia coli BL21(DE3) cells
Brugia malayi
Molecular Weight [Da]
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
5.4.2.12
61779
-
MALDI-TOF mass spectrometry
Brugia malayi
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
5.4.2.12
2-phospho-D-glycerate
Brugia malayi
-
3-phospho-D-glycerate
-
-
r
5.4.2.12
3-phospho-D-glycerate
Brugia malayi
-
2-phospho-D-glycerate
-
-
r
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
5.4.2.12
Brugia malayi
-
-
-
Purification (Commentary)
EC Number
Commentary
Organism
5.4.2.12
Ni-NTA agarose column chromatography
Brugia malayi
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
5.4.2.12
larva
-
Brugia malayi
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.4.2.12
2-phospho-D-glycerate
-
747238
Brugia malayi
3-phospho-D-glycerate
-
-
-
r
5.4.2.12
3-phospho-D-glycerate
-
747238
Brugia malayi
2-phospho-D-glycerate
-
-
-
r
Subunits
EC Number
Subunits
Commentary
Organism
5.4.2.12
monomer
1 * 60000, SDS-PAGE
Brugia malayi
Cofactor
EC Number
Cofactor
Commentary
Organism
Structure
5.4.2.12
additional information
the enzyme is independent from 2,3-bisphosphoglycerate
Brugia malayi
Cloned(Commentary) (protein specific)
EC Number
Commentary
Organism
5.4.2.12
expressed in Escherichia coli BL21(DE3) cells
Brugia malayi
Cofactor (protein specific)
EC Number
Cofactor
Commentary
Organism
Structure
5.4.2.12
additional information
the enzyme is independent from 2,3-bisphosphoglycerate
Brugia malayi
Molecular Weight [Da] (protein specific)
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
5.4.2.12
61779
-
MALDI-TOF mass spectrometry
Brugia malayi
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
5.4.2.12
2-phospho-D-glycerate
Brugia malayi
-
3-phospho-D-glycerate
-
-
r
5.4.2.12
3-phospho-D-glycerate
Brugia malayi
-
2-phospho-D-glycerate
-
-
r
Purification (Commentary) (protein specific)
EC Number
Commentary
Organism
5.4.2.12
Ni-NTA agarose column chromatography
Brugia malayi
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
5.4.2.12
larva
-
Brugia malayi
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.4.2.12
2-phospho-D-glycerate
-
747238
Brugia malayi
3-phospho-D-glycerate
-
-
-
r
5.4.2.12
3-phospho-D-glycerate
-
747238
Brugia malayi
2-phospho-D-glycerate
-
-
-
r
Subunits (protein specific)
EC Number
Subunits
Commentary
Organism
5.4.2.12
monomer
1 * 60000, SDS-PAGE
Brugia malayi