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Literature summary extracted from
- Ferrochelatase activity of plant frataxin (2019), Biochimie, 156, 118-122 .
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 4.98.1.1 | mitochondrion | - |
Arabidopsis thaliana | 5739 | - |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.98.1.1 | Arabidopsis thaliana | Q9ZR07 | cf. EC 1.16.3.1 | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 4.98.1.1 | 3.08 | - |
pH 8.0, 25°C | Arabidopsis thaliana |
| 4.98.1.1 | 4.8 | - |
presence of cysteine desulfurase NFS1 and small mitochondrial protein ISD11, pH 8.0, 25°C | Arabidopsis thaliana |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.98.1.1 | protoporphyrin IX + Fe2+ | - |
Arabidopsis thaliana | protoheme + 2 H+ | - |
? |  |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 4.98.1.1 | frataxin | - |
Arabidopsis thaliana |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 4.98.1.1 | physiological function | frataxin catalyzes the formation of heme in vitro when it is incubated with iron and protoporphyrin IX. In combination with cysteine desulfurase NFS1 and small mitochondrial protein ISD11 the ferrochelatase activity is increased | Arabidopsis thaliana |
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Release 2023.1 (January 2023)
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